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U2AF2 gene
Known as:
U2 small nuclear RNA auxiliary factor 2
, U2 small nuclear ribonucleoprotein auxiliary factor (65kD)
, U2AF65
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National Institutes of Health
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Papers overview
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Highly Cited
2012
Highly Cited
2012
CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo
Bo Gu
,
D. Eick
,
O. Bensaude
Nucleic Acids Research
2012
Corpus ID: 16342148
Co-transcriptional pre-mRNA processing relies on reversible phosphorylation of the carboxyl-terminal domain (CTD) of Rpb1, the…
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Highly Cited
2011
Highly Cited
2011
The RNA polymerase II C-terminal domain promotes splicing activation through recruitment of a U2AF65-Prp19 complex.
Charles J. David
,
A. Boyne
,
S. Millhouse
,
J. Manley
Genes & Development
2011
Corpus ID: 20744862
Pre-mRNA splicing is frequently coupled to transcription by RNA polymerase II (RNAPII). This coupling requires the C-terminal…
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Highly Cited
2003
Highly Cited
2003
Structural basis for the molecular recognition between human splicing factors U2AF65 and SF1/mBBP.
Philipp Selenko
,
G. Gregorovic
,
+4 authors
M. Sattler
Molecules and Cells
2003
Corpus ID: 34226795
Highly Cited
1999
Highly Cited
1999
Pre-mRNA splicing of IgM exons M1 and M2 is directed by a juxtaposed splicing enhancer and inhibitor.
J. Kan
,
M. Green
Genes & Development
1999
Corpus ID: 35488930
Splicing of certain pre-mRNA introns is dependent on an enhancer element, which is typically purine-rich. It is generally thought…
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Highly Cited
1998
Highly Cited
1998
A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition.
J. Berglund
,
N. Abovich
,
Michael Rosbash
Genes & Development
1998
Corpus ID: 6688329
During the early events of pre-mRNA splicing, intronic cis-acting sequences are recognized and interact through a network of RNA…
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Highly Cited
1998
Highly Cited
1998
WT1 interacts with the splicing factor U2AF65 in an isoform-dependent manner and can be incorporated into spliceosomes.
Rachel Davies
,
C. Calvio
,
Eva Bratt
,
Stefan H. Larsson
,
A. Lamond
,
Nicholas D. Hastie
Genes & Development
1998
Corpus ID: 8608531
WT1 is essential for normal kidney development, and genetic alterations are associated with Wilms' tumor, Denys Drash (DDS), and…
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Highly Cited
1997
Highly Cited
1997
Cross-Intron Bridging Interactions in the Yeast Commitment Complex Are Conserved in Mammals
N. Abovich
,
M. Rosbash
Cell
1997
Corpus ID: 18466775
Highly Cited
1996
Highly Cited
1996
The splicing factor U2AF35 mediates critical protein-protein interactions in constitutive and enhancer-dependent splicing.
P. Zuo
,
T. Maniatis
Genes & Development
1996
Corpus ID: 46665177
The splicing factor U2AF (U2 snRNP auxiliary factor) is a heterodimer with subunits of 65 and 35 kD (U2AF65 and U2AF35). U2AF65…
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Highly Cited
1994
Highly Cited
1994
The yeast MUD2 protein: an interaction with PRP11 defines a bridge between commitment complexes and U2 snRNP addition.
N. Abovich
,
Xiaoling C. Liao
,
Michael Rosbash
Genes & Development
1994
Corpus ID: 32292210
In characterizing a series of yeast (Saccharomyces cerevisiae) mutants synthetic lethal with U1 RNA, we have identified a yeast…
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Highly Cited
1992
Highly Cited
1992
Protein components specifically associated with prespliceosome and spliceosome complexes.
M. Bennett
,
S. Michaud
,
J. Kingston
,
R. Reed
Genes & Development
1992
Corpus ID: 46137540
We have carried out a systematic analysis of the protein composition of highly purified mammalian spliceosomes. We show that > 30…
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