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A logical analysis of the Drosophila gap-gene system.
This manuscript focuses on the formal analysis of the gap-gene network involved in Drosophila segmentation. The gap genes are expressed in defined domains along the anterior-posterior axis of theExpand
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Sex-determining mechanisms in insects.
  • L. Sánchez
  • Biology, Medicine
  • The International journal of developmental…
  • 2008
Sex determination refers to the developmental programme that commits the embryo to either the male or the female pathway. The animal kingdom possesses a wealth of mechanisms via which gender isExpand
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The gene transformer-2 of Anastrepha fruit flies (Diptera, Tephritidae) and its evolution in insects
Background In the tephritids Ceratitis, Bactrocera and Anastrepha, the gene transformer provides the memory device for sex determination via its auto-regulation; only in females is functional TraExpand
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The gene transformer-2 of Sciara (Diptera, Nematocera) and its effect on Drosophila sexual development
BackgroundThe gene transformer-2, which is involved in sex determination, has been studied in Drosophila, Musca, Ceratitis, Anastrepha and Lucilia. All these members of Diptera belong to the suborderExpand
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Evidence of a dual function in fl(2)d, a gene needed for Sex-lethal expression in Drosophila melanogaster.
In Drosophila melanogaster, the female sexual development of the soma and the germline requires the activity of the gene Sxl. The somatic cells need the function of the gene fl(2)d to follow theExpand
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Sex determination genes control the development of the Drosophila genital disc, modulating the response to Hedgehog, Wingless and Decapentaplegic signals.
In both sexes, the Drosophila genital disc contains the female and male genital primordia. The sex determination gene doublesex controls which of these primordia will develop and which will beExpand
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Biochemical Function of Female-Lethal (2)D/Wilms' Tumor Suppressor-1-associated Proteins in Alternative Pre-mRNA Splicing*
Genetic and molecular data have implicated theDrosophila gene female-lethal (2)d (fl (2)d) in alternative splicing regulation of genes involved in sexual determination. Sex-specific splicing is underExpand
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Genetic Coadaptation in the Chromosomal Polymorphism of DROSOPHILA SUBOBSCURA. I. Seasonal Changes of Gametic Disequilibrium in a Natural Population.
Seasonal changes in gene arrangement and allozyme frequencies have been investigated in Drosophila subobscura for several years. Some arrangements (O(st) and O(3+4+7)) show seasonal variation, whichExpand
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The genital disc of Drosophila melanogaster
Abstract The genital disc consists of three primordia: the female genital, the male genital and the anal primordia. In individuals of either sex, only one of the two genital primordia grows, whereasExpand
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The gene doublesex of Anastrepha fruit flies (Diptera, Tephritidae) and its evolution in insects
The doublesex (dsx) gene of several Anastrepha species was isolated and characterised. Its molecular organisation was found to be the same in all the species examined. This gene is composed of fourExpand
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