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U 80244

Known as: U-80244 
National Institutes of Health

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1 relation

Broader (1)

carzelesin

Papers overview

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1996
1996
Phase I clinical and pharmacokinetic study of carzelesin (U-80244) given daily for five consecutive days.
Carzelesin (U-80244), one of the synthetic DNA minor groove binding cyclopropylpyrroloindole analogues, was selected for clinical… 
1993
1993
In vitro evaluation of the novel chemotherapeutic agents U-73,975, U-77,779, and U-80,244 in gynecologic cancer cell lines.
U-73,975 (U-73), U-77,779 (U-77), and U-80,244 (U-80) are analogs of the potent antitumor compound CC-1065. This class of drugs… 
Highly Cited
1992
Highly Cited
1992
Cytotoxicity and antitumor activity of carzelesin, a prodrug cyclopropylpyrroloindole analogue.
The cyclopropylpyrroloindole analogues are DNA minor-groove binders containing a cyclopropyl group, which mediates N3-adenine… 
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