Skip to search formSkip to main contentSkip to account menu

U 75412E

Known as: Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(3-(ethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, (Z)-2-butenedioate (1:1), U-75412E, U75412E 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

Steroids

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
Suppressive effects of a novel antioxidant compound on human T cell functionsin vitro
The use of antioxidant compounds with differing modes of action has clearly demonstrated involvement of oxidative processes in… 
2000
2000
Modulation of microvascular permeability by 21-aminosteroids after burn injuries.
Burn injuries initiate lipid peroxidation in capillary endothelial cells and cause alterations in microvascular permeability… 
1999
1999
Early Alterations of Lung Injury Following Acute Smoke Exposure and 21-Aminosteroid Treatment
In a simulated fire-related smoke exposure protocol, New Zealand white rabbits were utilized to investigate the potential effects… 
1999
1999
Functional alterations of alveolar macrophages subjected to smoke exposure and antioxidant lazaroids
Acute inhalation of diesel fuel-polycarbonate plastic (DFPP) smoke causes severe lung injury, leading to acute respiratory… 
1998
1998
Antioxidant activity of lazaroid (U-75412E) and its protective effects against crystalline silica-induced cytotoxicity.
1997
1997
A free radical scavenger (Lazaroid U75412E) attenuates tumor necrosis factor-alpha generation in a rabbit model of smoke-induced lung injury.
The lazaroid (21-aminosteroid) analogue U75412E was evaluated in rabbits exposed to diesel fuel-polycarbonate plastic smoke… 
1996
1996
The prophylactic effects of U75412E pretreatment in a smoke-induced lung injury rabbit model.
The effects of the lazaroid analogue U75412E (21-[4-(3-ethylamino-2-pyridinyl)-1-piperazinyl]-16 alpha-methylpregna-1,4,9]-(11… 
1994
1994
Effects of 21-aminosteroids in neonatal rat cardiac myocyte cell cultures exposed to free radicals.
OBJECTIVE The aim was to test a group of 21-aminosteroids, U74006F, U75412E, and U74500E, known as lazaroids, for their ability… 
Highly Cited
1993
Highly Cited
1993
U75412E, a lazaroid, prevents progressive burn ischemia in a rat burn model.
Thermal energy causes an immediate, irreversible injury at the burn site, followed by a delayed, reversible tissue loss in the… 
1991
1991
Intravitreal U75412E: a new free radical scavenger.
Free-radical-mediated tissue damage is thought to be involved in a multitude of ophthalmic pathologies. Therefore, drugs that… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)