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U 75412E

Known as: Pregna-1,4,9(11)-triene-3,20-dione, 21-(4-(3-(ethylamino)-2-pyridinyl)-1-piperazinyl)-16-methyl-, (16alpha)-, (Z)-2-butenedioate (1:1), U-75412E, U75412E 
 
National Institutes of Health

Papers overview

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2000
2000
Burn injuries initiate lipid peroxidation in capillary endothelial cells and cause alterations in microvascular permeability… Expand
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1999
1999
In a simulated fire-related smoke exposure protocol, New Zealand white rabbits were utilized to investigate the potential effects… Expand
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1999
1999
Acute inhalation of diesel fuel-polycarbonate plastic (DFPP) smoke causes severe lung injury, leading to acute respiratory… Expand
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1998
1998
Lazaroids (21-amino steroids) are believed to be powerful scavengers of reactive oxygen species (ROS) and inhibitors of lipid… Expand
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1997
1997
The lazaroid (21-aminosteroid) analogue U75412E was evaluated in rabbits exposed to diesel fuel-polycarbonate plastic smoke… Expand
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1996
1996
The effects of the lazaroid analogue U75412E (21-[4-(3-ethylamino-2-pyridinyl)-1-piperazinyl]-16 alpha-methylpregna-1,4,9]-(11… Expand
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1994
1994
The 21-aminosteroids (or lazaroids) are a recently synthesized class of compounds demonstrated to protect tissue against damage… Expand
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Highly Cited
1993
Highly Cited
1993
Thermal energy causes an immediate, irreversible injury at the burn site, followed by a delayed, reversible tissue loss in the… Expand
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1992
1992
Lazaroids are potent inhibitors of lipid peroxidation. Endothelial cell damage has been shown to occur during cold storage… Expand
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1991
1991
The lipid peroxidation inhibitors U74006F (21-[4-(2,6-di-1-pyrrolidinyl-4-pyrimidinyl)-1-piperazinyl]-16 alpha-methylpregna-1,4,9… Expand
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