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Tunicamycin

Known as: Tunicamycin [Chemical/Ingredient] 
An N-acetylglycosamine containing antiviral antibiotic obtained from Streptomyces lysosuperificus. It is also active against some bacteria and fungi… 
National Institutes of Health

Related topics

Related topics

20 relations

Broader (5)

Anti-Bacterial AgentsAntibiotics, AntineoplasticAntiviral AgentsNucleoside Analogs
Glycoprotein biosynthetic processIn BloodN-Glycan Biosynthesis PathwayProcess of secretion

Narrower (3)

tunicamycin A1tunicamycin B2tunicamycin B3

Papers overview

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Highly Cited
1991
Highly Cited
1991
Ethylene Biosynthesis-Inducing Xylanase : II. Purification and Physical Characterization of the Enzyme Produced by Trichoderma viride.
The ethylene biosynthesis-inducing endoxylanase (EIX) from xylan-induced cultures of the fungus, Trichoderma viride, was purified… 
1985
1985
Isolation of tyrosine-O-sulfate by Pronase hydrolysis from fibronectin secreted by Fujinami sarcoma virus-infected rat fibroblasts.
In a recent paper, we reported the loss of large amounts of protein-bound tyrosine sulfate after infection of rat fibroblasts by… 
1983
1983
Tunicamycin inhibits ganglioside biosynthesis in neuronal cells.
The antibiotic tunicamycin blocks the transfer of GlcNAc-1-P from UDP-GlcNAc to dolichol phosphate, thereby blocking the… 
Highly Cited
1983
Highly Cited
1983
Biosynthesis and transport of lysosomal enzymes in human monocytes and macrophages. Effects of ammonium chloride, zymosan and tunicamycin.
Human monocytes and macrophages synthesize lysosomal enzymes as larger precursors. The polypeptide patterns of several lysosomal… 
1983
1983
Glycosylation of herpes simplex virus type 1 gC in the presence of tunicamycin
The presence of O-glycosidic linkages on herpes simplex virus type 1 (HSV-1) glycoproteins was indicated by the synthesis and… 
1980
1980
Tunicamycin inhibits mouse tooth morphogenesis and odontoblast differentiation in vitro.
Tunicamycin (TM), an antibiotic that selectively inhibits dolichol-mediated protein glycosylation, inhibited morphogenesis and… 
1980
1980
Inhibition of fibronectin-mediated adhesion of hamster fibroblasts to substratum: effects of tunicamycin and some cell surface modifying reagents.
Using baby hamster kidney (BHK) fibroblasts we have studied the effect of tunicamycin, a specific inhibitor of protein… 
1979
1979
Effect of tunicamycin on transport of lysosomal enzymes in cultured skin fibroblasts.
After an initial lag phase, tunicamycin (0.12–3.6 μM) inhibits the secretion of β-N-acetylglucosaminidase by human skin… 
Highly Cited
1978
Highly Cited
1978
Effects of tunicamycin on the biosynthesis of glycosaminoglycans by embryonic chick cornea.
The antibiotic, tunicamycin, was used to investigate the possible involvement of lipid-saccharide intermediates in the… 
1978
1978
Tunicamycin-resistant mutants and chromosomal locations of mutational sites in Bacillus subtilis
The types of tunicamycin-resistant mutants of Bacillus subtilis were analyzed, and their mutational sites on the chromosome were… 
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