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Tumor necrosis factor receptor 11b

Known as: Tumor Necrosis Factor Receptor Superfamily, Member 11b, FDCR 1 Protein, Receptors, Tumor Necrosis Factor, Member 11b 
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that… 
National Institutes of Health

Related topics

Related topics

15 relations
In BloodOsteoprotegerin testProcess of secretionReceptor Activator of Nuclear Factor-kappa B

Broader (1)

Receptors, Cytokine

Narrower (2)

TNFRSF11B protein, humanTnfrsf11b protein, mouse

Papers overview

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Highly Cited
2012
Highly Cited
2012
Erythropoietin modulates the structure of bone morphogenetic protein 2-engineered cranial bone.
The ideally engineered bone should have similar structural and functional properties to the native tissue. Although structural… 
2009
2009
One Year of Transgenic Overexpression of Osteoprotegerin in Rats Suppressed Bone Resorption and Increased Vertebral Bone Volume, Density, and Strength
RANKL is an essential mediator of bone resorption, and its activity is inhibited by osteoprotegerin (OPG). Transgenic (Tg) rats… 
Highly Cited
2007
Highly Cited
2007
An osteoprotegerin-like peptidomimetic inhibits osteoclastic bone resorption and osteolytic bone disease in myeloma.
Multiple myeloma is a B-cell malignancy characterized by the uncontrolled growth of plasma cells in the bone marrow and the… 
Highly Cited
2007
Highly Cited
2007
The “lively” cytokines network in β-Thalassemia Major-related osteoporosis
Highly Cited
2007
Highly Cited
2007
Inhibition of tooth movement by osteoprotegerin vs. pamidronate under conditions of constant orthodontic force.
The undesired movement of anchor teeth, and relapse of previously moved teeth, are major clinical problems in orthodontics… 
2007
2007
Attenuation of Bone Mass and Increase of Osteoclast Formation in Decoy Receptor 3 Transgenic Mice*
Decoy receptor 3 (DcR3), a soluble receptor for FasL, LIGHT, and TL1A, induces osteoclast formation from monocyte, macrophage… 
Highly Cited
2006
Highly Cited
2006
Resorption of auditory ossicles and hearing loss in mice lacking osteoprotegerin.
Highly Cited
2005
Highly Cited
2005
Relationship of serum osteoprotegerin levels with coronary artery disease severity, left ventricular hypertrophy and C-reactive protein.
OPG (osteoprotegerin) is an inhibitor of osteoclastogenesis and recent work suggests it has a role in atherosclerosis. Therefore… 
Highly Cited
2004
Highly Cited
2004
Susceptibility to Paget's Disease of Bone Is Influenced by a Common Polymorphic Variant of Osteoprotegerin
To clarify the role of the TNFRSF11B gene encoding osteoprotegerin (OPG), in Paget's disease of bone (PDB) we studied TNFRSF11B… 
Review
1998
Review
1998
Osteoprotegerin and its cognate ligand: a new paradigm of osteoclastogenesis.
Osteoprotegerin (OPG) has recently been identified as a new member of the tumor necrosis factor (TNF)receptor (TNF-R) superfamily… 
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