Tumor necrosis factor receptor 11b

Known as: Tumor Necrosis Factor Receptor Superfamily, Member 11b, FDCR 1 Protein, Receptors, Tumor Necrosis Factor, Member 11b 
A secreted member of the TNF receptor superfamily that negatively regulates osteoclastogenesis. It is a soluble decoy receptor of RANK LIGAND that… (More)
National Institutes of Health

Related topics

Related topics

15 relations
In BloodOsteoprotegerin testProcess of secretionReceptor Activator of Nuclear Factor-kappa B
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Broader (1)

Receptors, Cytokine

Narrower (2)

TNFRSF11B protein, humanTnfrsf11b protein, mouse

Papers overview

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Review
2001
Review
2001
Role of receptor activator of nuclear factor-κB ligand and osteoprotegerin in bone cell biology
Receptor activator of nuclear factor (NF-κB) ligand (RANKL), its cellular receptor, receptor activator of NF-κB (RANK), and the… (More)
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Highly Cited
2001
Highly Cited
2001
Differential expression of bone matrix regulatory proteins in human atherosclerotic plaques.
In the present study, we examined the expression of regulators of bone formation and osteoclastogenesis in human atherosclerosis… (More)
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Highly Cited
1999
Highly Cited
1999
Activated T cells regulate bone loss and joint destruction in adjuvant arthritis through osteoprotegerin ligand
Bone remodelling and bone loss are controlled by a balance between the tumour necrosis factor family molecule osteoprotegerin… (More)
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Highly Cited
1999
Highly Cited
1999
Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells.
Recent studies have identified osteoprotegerin ligand (OPG-L) as the essential factor required for osteoclastogenesis, and that… (More)
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Highly Cited
1998
Highly Cited
1998
Osteoprotegerin is a receptor for the cytotoxic ligand TRAIL.
TRAIL is a tumor necrosis factor-related ligand that induces apoptosis upon binding to its death domain-containing receptors, DR4… (More)
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Highly Cited
1998
Highly Cited
1998
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKL.
Osteoclasts, the multinucleated cells that resorb bone, develop from hematopoietic cells of monocyte/macrophage lineage… (More)
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Highly Cited
1998
Highly Cited
1998
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification.
Osteoprotegerin (OPG) is a secreted protein that inhibits osteoclast formation. In this study the physiological role of OPG is… (More)
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Highly Cited
1998
Highly Cited
1998
Osteoprotegerin Ligand Is a Cytokine that Regulates Osteoclast Differentiation and Activation
The ligand for osteoprotegerin has been identified, and it is a TNF-related cytokine that replaces the requirement for stromal… (More)
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Highly Cited
1998
Highly Cited
1998
Identity of osteoclastogenesis inhibitory factor (OCIF) and osteoprotegerin (OPG): a mechanism by which OPG/OCIF inhibits osteoclastogenesis in vitro.
The morphogenesis and remodeling of bone depends on the integrated activity of osteoblasts that form bone and osteoclasts that… (More)
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Highly Cited
1997
Highly Cited
1997
Osteoprotegerin: A Novel Secreted Protein Involved in the Regulation of Bone Density
A novel secreted glycoprotein that regulates bone resorption has been identified. The protein, termed Osteoprotegerin (OPG), is a… (More)
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