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Tubulointerstitial fibrosis

Known as: Renal interstitial fibrosis 
Fibrosis that involves the tubules and interstitial tissue of the kidney. [HPO:probinson, pmid:19144691]
National Institutes of Health

Related topics

Related topics

1 relation
Medullary cystic kidney disease 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Epithelial—mesenchymal transdifferentiation of renal tubular epithelial cells induced by urinary proteins requires the activation of PKC‐α and βI isozymes
Proteinuria is a common feature for almost all glomerular diseases and reflects the severity of the glomerular lesion. The… 
Review
2009
Review
2009
Peroxisome Proliferator-Activated Receptor Gamma Agonists in Kidney Disease – Future Promise, Present Fears
  • Z. MaoA. Ong
  • Nephron Clinical Practice
  • 2009
  • Corpus ID: 7969049
The peroxisome proliferator-activated receptor superfamily (PPARs) comprises a class of nuclear receptors with significant… 
2005
2005
Differential immunoexpressions of cytoskeletons in renal epithelial and interstitial cells in rat and canine fibrotic kidneys, and in kidney-related cell lines under fibrogenic stimuli.
2005
2005
Cisplatin-Induced Renal Interstitial Fibrosis in Neonatal Rats, Developing as Solitary Nephron Unit Lesions
Cisplatin (CDDP)-induced renal lesions in rats prove a useful model for analysis of the pathogenesis of post-tubular injury-renal… 
2003
2003
Possible involvement of mitogen-activated protein kinase in the angiotensin II-induced fibronectin synthesis in renal interstitial fibroblasts.
Review
2002
Review
2002
Cellular and molecular events leading to renal tubulointerstitial fibrosis
 Connective tissue remodeling of the extracellular matrix (ECM) is an essential and dynamic process associated with both… 
Highly Cited
1998
Highly Cited
1998
Tissue-specific regulation of growth factors and clusterin by angiotensin II.
1998
1998
Immunohistochemical Analysis of Macrophages, Myofibroblasts, and Transforming Growth Factor-β Localization during Rat Renal Interstitial Fibrosis Following Long-Term Unilateral Ureteral Obstruction
Renal interstitial fibrosis was induced in rats by chronic unilateral ureteral obstruction (UUO). To identify the mechanisms… 
Review
1996
Review
1996
Expression of genes that promote renal interstitial fibrosis in rats with proteinuria.
The development of progressive tubular atrophy and interstitial fibrosis represents a final common pathway leading to renal… 
Highly Cited
1993
Highly Cited
1993
Human renal tubular cells as a cytokine source: PDGF-B, GM-CSF and IL-6 mRNA expression in vitro.
The pathogenesis of renal interstitial fibrosis is not fully understood at present. As renal interstitial fibrosis occurs mainly… 
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