Tubulointerstitial fibrosis

Known as: Renal interstitial fibrosis 
Fibrosis that involves the tubules and interstitial tissue of the kidney. [HPO:probinson, pmid:19144691]
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Members of the miR-200 family of micro RNAs (miRNAs) have been shown to inhibit epithelial-mesenchymal transition (EMT). EMT of… (More)
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Highly Cited
2010
Highly Cited
2010
Chronic kidney disease is a leading cause of death in the United States. Tubulointerstitial fibrosis (TIF) is considered the… (More)
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Highly Cited
2009
Highly Cited
2009
Significant reduction of renal mass initiates a series of hemodynamic and nonhemodynamic events which lead to proteinuria… (More)
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Highly Cited
2007
Highly Cited
2007
Hypoxia has been proposed as an important microenvironmental factor in the development of tissue fibrosis; however, the… (More)
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Highly Cited
2006
Highly Cited
2006
Deficiency in vitamin D and its active metabolites is a pathologic feature of chronic kidney diseases. Despite that tubular… (More)
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Highly Cited
2001
Highly Cited
2001
The infiltration of leukocytes plays a major role in mediating tubulointerstitial inflammation and fibrosis in chronic renal… (More)
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Highly Cited
1998
Highly Cited
1998
Chronic renal disease (CRD) is generally thought to be incurable, except through renal transplantation, and the number of… (More)
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Highly Cited
1997
Highly Cited
1997
Transgenic mice overexpressing a constitutively active human TGF-beta1 under control of the rat phosphoenolpyruvate carboxykinase… (More)
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Review
1996
Review
1996
Progressive interstitial fibrosis accompanied by loss of renal tubules and interstitial capillaries typifies all progressive… (More)
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Highly Cited
1995
Highly Cited
1995
Unilateral ureteral obstruction (UUO) results in tubulointerstitial fibrosis of the obstructed kidney (OBK). In this study we… (More)
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