Tubulin Inhibitors

Known as: Tubulin Polymerization Inhibitors, Polymerization Inhibitors, Tubulin, Inhibitors, Tubulin 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2013-2017
02420132017

Papers overview

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Review
2016
Review
2016
INTRODUCTION Microtubules represent one of the most logical and strategic molecular targets amongst the current targets for… (More)
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Review
2016
Review
2016
Extensive research over the last decade has resulted in a number of highly potent tubulin polymerization inhibitors acting either… (More)
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Review
2016
Review
2016
Tubulin inhibitors are effective anticancer agents, however, there are many limitations to the use of available tubulin… (More)
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Review
2016
Review
2016
Discovery of new indole-based tubulin polymerization inhibitors will continue to dominate the synthetic efforts of many medicinal… (More)
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2015
2015
A series of 1-benzene acyl-2-(1-methylindol-3-yl)-benzimidazole derivatives were designed, synthesized and evaluated as potential… (More)
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2015
2015
Thirteen new N-aryl 1,2,3,4-tetrahydroquinoline compounds (4a-f, 6a-c, and 8a-d) were synthesized and evaluated for antitumor… (More)
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2015
2015
We recently reported that CMPD1, originally developed as an inhibitor of MK2 activation, primarily inhibits tubulin… (More)
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2014
2014
Emerging drug resistance and other drawbacks limit tubulin inhibitors' therapeutic applications and developing novel tubulin… (More)
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Review
2014
Review
2014
Microtubules are protein biopolymers formed through polymerization of heterodimers of α- and β-tubulins. Disruption of… (More)
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2013
2013
Structural optimizations of the prior lead 1a led to the discovery of a series of N-aryl-6-methoxy-1,2,3,4-tetrahydroquinoline… (More)
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