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Trypanosoma cruzi

Known as: cruzi trypanosoma, American trypanosome, Trypanosoma cruzus 
A species of parasitic euglenoid protozoan in the family Trypanosomatidae. T. cruzi is passed between mammalian hosts through the feces of a… 
National Institutes of Health

Related topics

Related topics

17 relations
CDISC SDTM Microorganism TerminologyChagas DiseaseClinical Data Interchange Standards Consortium TerminologyMicrobiological

Broader (1)

Trypanosoma

Papers overview

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Highly Cited
2006
Highly Cited
2006
Cutting Edge: TLR9 and TLR2 Signaling Together Account for MyD88-Dependent Control of Parasitemia in Trypanosoma cruzi Infection1
Activation of innate immune cells by Trypanosoma cruzi-derived molecules such as GPI anchors and DNA induces proinflammatory… 
Highly Cited
2005
Highly Cited
2005
Comparative analysis of the kinomes of three pathogenic trypanosomatids: Leishmania major, Trypanosoma brucei and Trypanosoma cruzi
BackgroundThe trypanosomatids Leishmania major, Trypanosoma brucei and Trypanosoma cruzi cause some of the most debilitating… 
Highly Cited
2000
Highly Cited
2000
Host Cell Invasion by TRYPANOSOMA cRUZI Is Potentiated by Activation of Bradykinin B2 Receptors
The parasitic protozoan Trypanosoma cruzi employs multiple molecular strategies to invade a broad range of nonphagocytic cells… 
Highly Cited
1998
Highly Cited
1998
Defective Nitric Oxide Effector Functions Lead to Extreme Susceptibility of Trypanosoma cruzi-Infected Mice Deficient in Gamma Interferon Receptor or Inducible Nitric Oxide Synthase
ABSTRACT Trypanosoma cruzi, the causative agent of Chagas’ disease, induces an innate and adaptive host immune response during… 
Highly Cited
1997
Highly Cited
1997
IL-10 is required to prevent immune hyperactivity during infection with Trypanosoma cruzi.
Previous studies have associated the production of IL-10 with suppression of the protective cell-mediated immune response to… 
Highly Cited
1996
Highly Cited
1996
Interleukin-12 mediates resistance to Trypanosoma cruzi in mice and is produced by murine macrophages in response to live trypomastigotes
Host resistance to infection by Trypanosoma cruzi is dependent on both natural and acquired immune responses. During the first… 
Highly Cited
1995
Highly Cited
1995
Tumor necrosis factor alpha mediates resistance to Trypanosoma cruzi infection in mice by inducing nitric oxide production in infected gamma interferon-activated macrophages
Cell invasion by Trypanosoma cruzi and its intracellular replication are essential for continuation of the parasite life cycle… 
Highly Cited
1994
Highly Cited
1994
Cytosolic-free calcium elevation in Trypanosoma cruzi is required for cell invasion
To replicate, the trypomastigote form of Trypanosoma cruzi must invade host cells. Since a role for Ca2+ in the process of cell… 
Highly Cited
1992
Highly Cited
1992
Interleukin 10 and interferon gamma regulation of experimental Trypanosoma cruzi infection
Studies were undertaken to determine whether interleukin 10, (IL-10) a cytokine shown to inhibit interferon gamma (IFN-gamma… 
Highly Cited
1986
Highly Cited
1986
Natural populations of Trypanosoma cruzi, the agent of Chagas disease, have a complex multiclonal structure.
We have studied 15 gene loci coding for enzymes in 121 Trypanosoma cruzi stocks from a wide geographic range--from the United… 
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