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Trp-Lys-Tyr-Met-Val-Met

Known as: WKYMVM, tryptophyl-lysyl-tyrosyl-methionyl-valyl-methionyl 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Oligopeptides

Narrower (1)

Trp-Lys-Tyr-Met-Val-DMet

Papers overview

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Highly Cited
2005
Highly Cited
2005
Serum amyloid A stimulates matrix-metalloproteinase-9 upregulation via formyl peptide receptor like-1-mediated signaling in human monocytic cells.
Highly Cited
2004
Highly Cited
2004
Urokinase Induces Basophil Chemotaxis through a Urokinase Receptor Epitope That Is an Endogenous Ligand for Formyl Peptide Receptor-Like 1 and -Like 21
Basophils circulate in the blood and are able to migrate into tissues at sites of inflammation. Urokinase plasminogen activator… 
Highly Cited
2004
Highly Cited
2004
The mechanism for activation of the neutrophil NADPH‐oxidase by the peptides formyl‐Met‐Leu‐Phe and Trp‐Lys‐Tyr‐Met‐Val‐Met differs from that for interleukin‐8
Neutrophil chemotaxis has been shown to be regulated by two different signalling pathways that allow strong chemoattractants… 
2003
2003
Histamine Inhibits Neutrophil NADPH Oxidase Activity Triggered by the Lipoxin A4 Receptor‐Specific Peptide Agonist Trp‐Lys‐Tyr‐Met‐Val‐Met
The vasoactive amine histamine is found at high concentrations in the immune and inflammatory tissues. Earlier studies have… 
Highly Cited
2000
Highly Cited
2000
The Synthetic Peptide Trp-Lys-Tyr-Met-Val-d-Met Is a Potent Chemotactic Agonist for Mouse Formyl Peptide Receptor1
Formyl peptides are potent neutrophil chemoattractants. In humans and rabbits, the formyl peptide receptor (FPR) binds N-formyl… 
2000
2000
Independent Functioning of Cytosolic Phospholipase A2 and Phospholipase D1 in Trp-Lys-Tyr-Met-Val-D-Met-Induced Superoxide Generation in Human Monocytes1
Recently, a novel peptide (Trp-Lys-Tyr-Met-Val-D-Met, WKYMVm) has been shown to induce superoxide generation in human monocytes… 
Highly Cited
1999
Highly Cited
1999
Trp‐Lys‐Tyr‐Met‐Val‐D‐Met stimulates superoxide generation and killing of Staphylococcus aureus via phospholipase D activation in human monocytes
Among the phagocytic leukocytes, monocytes have the important role of clearing out parasitic microorganisms. They accomplish this… 
1999
1999
Trp‐Lys‐Tyr‐Met‐Val‐d‐Met is a chemoattractant for human phagocytic cells
Trp‐Lys‐Tyr‐Met‐Val‐d‐Met (WKYMVm) is a synthetic peptide that stimulates phosphoinosi‐tide (PI) hydrolysis in human leukocytes… 
Highly Cited
1997
Highly Cited
1997
A peptide with unique receptor specificity: stimulation of phosphoinositide hydrolysis and induction of superoxide generation in human neutrophils.
Previously, we identified peptides that stimulate phosphoinositide hydrolysis in several leukocyte cell lines from mixtures of… 
Highly Cited
1996
Highly Cited
1996
Identification of the Peptides That Stimulate the Phosphoinositide Hydrolysis in Lymphocyte Cell Lines from Peptide Libraries (*)
Peptides which stimulate the formation of inositol phosphates (InoPs) in lymphocyte cell lines were identified by screening… 
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