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Troponin T, Cardiac Muscle

Known as: cTnT, TnTc, Cardiac Muscle Troponin T 
Troponin T, cardiac muscle (298 aa, ~36 kDa) is encoded by the human TNNT2 gene. This protein plays a role in cardiac muscle contraction.
National Institutes of Health

Related topics

Related topics

17 relations
Cardiac Muscle ContractionCell MovementCytokinesisCytoplasmic matrix
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Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
One-hour rule-out and rule-in of acute myocardial infarction using high-sensitivity cardiac troponin T.
BACKGROUND High-sensitivity cardiac troponin (hs-cTn) assays seem to improve the early diagnosis of acute myocardial infarction… Expand
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Highly Cited
2010
Highly Cited
2010
Analytical validation of a high-sensitivity cardiac troponin T assay.
BACKGROUND We report the development of a novel high-sensitivity cardiac troponin T (hs-cTnT) assay, a modification of the Roche… Expand
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Highly Cited
2010
Highly Cited
2010
Association of troponin T detected with a highly sensitive assay and cardiac structure and mortality risk in the general population.
CONTEXT Detectable levels of cardiac troponin T (cTnT) are strongly associated with structural heart disease and increased risk… Expand
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Highly Cited
2010
Highly Cited
2010
Association of serial measures of cardiac troponin T using a sensitive assay with incident heart failure and cardiovascular mortality in older adults.
CONTEXT Older adults comprise the majority of new-onset heart failure (HF) diagnoses, but traditional risk-factor prediction… Expand
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Highly Cited
2008
Highly Cited
2008
Cardiac troponin and outcome in acute heart failure.
BACKGROUND Cardiac troponin provides diagnostic and prognostic information in acute coronary syndromes, but its role in acute… Expand
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Highly Cited
2007
Highly Cited
2007
Prognostic Value of Very Low Plasma Concentrations of Troponin T in Patients With Stable Chronic Heart Failure
Background— Circulating cardiac troponin T, a marker of cardiomyocyte injury, predicts adverse outcome in patients with heart… Expand
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Highly Cited
2002
Highly Cited
2002
Predictive Value of Cardiac Troponin I and T for Subsequent Death in End-Stage Renal Disease
Background—This study determined the prevalence of increased cardiac troponin I (cTnI) and T (cTnT) in end-stage renal disease… Expand
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Highly Cited
1997
Highly Cited
1997
Cardiac troponin T in patients with clinically suspected myocarditis.
OBJECTIVES The present study investigated whether myocyte injury can be assessed sensitively by measurement of serum levels of… Expand
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Highly Cited
1992
Highly Cited
1992
The prognostic value of serum troponin T in unstable angina.
BACKGROUND Cardiac troponin T is a regulatory contractile protein not normally found in blood. Its detection in the circulation… Expand
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Highly Cited
1991
Highly Cited
1991
Intracellular compartmentation of cardiac troponin T and its release kinetics in patients with reperfused and nonreperfused myocardial infarction.
In a previous study on the diagnostic efficiency of troponin T measurements in patients with suspected acute myocardial… Expand
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