Tropomyosin Alpha-4 Chain

Known as: TM30p1, TPM4, Tropomyosin-4 
Tropomyosin alpha-4 chain (248 aa, ~29 kDa) is encoded by the human TPM4 gene. This protein is involved in both muscle contraction and actin… Expand
National Institutes of Health

Related topics

Related topics

10 relations
Actin myofilamentActin-Binding ProteinCell MovementCytokinesis
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Hypoxic regulation of RIOK3 is a major mechanism for cancer cell invasion and metastasis
Hypoxia is a common feature of locally advanced breast cancers that is associated with increased metastasis and poorer survival… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
2013
2013
LRRK2 guides the actin cytoskeleton at growth cones together with ARHGEF7 and Tropomyosin 4.
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene represent the most common genetic cause of Parkinson's disease (PD… Expand
Is this relevant?
2012
2012
Peroxiredoxins and tropomyosins as plasma biomarkers for lung cancer and asbestos exposure.
The prognosis of lung cancer is poor due to late diagnosis, the lack of established screening programs, and the paucity of early… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?
2011
2011
Differential expression of ANXA6, HSP27, PRDX2, NCF2, and TPM4 during uterine cervix carcinogenesis: diagnostic and prognostic value
Background:Cytology-based diagnostics of squamous cervical cancer (SCC) precursor lesions is subjective and can be improved by… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 3
  • table 3
Is this relevant?
2011
2011
The anti-cancer effects of (-)-epigallocatechin-3-gallate on the signaling pathways associated with membrane receptors in MCF-7 cells.
(-)-Epigallocatechin-3-gallate (EGCg) has been implicated in cancer chemo-prevention in studies using many different kinds of… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
2010
2010
Genetic association analysis highlights new loci that modulate hematological trait variation in Caucasians and African Americans
Red blood cell, white blood cell, and platelet measures, including their count, sub-type and volume, are important diagnostic and… Expand
  • figure 1
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Identification of breast cancer metastasis-associated proteins in an isogenic tumor metastasis model using two-dimensional gel electrophoresis and liquid chromatography-ion trap-mass spectrometry.
To better understand the molecular mechanisms underlying breast cancer metastasis and search for potential markers for metastatic… Expand
Is this relevant?
Highly Cited
2005
Highly Cited
2005
Comparative proteomic analysis of esophageal squamous cell carcinoma.
Ranking as the fourth commonest cancer, esophageal squamous cell carcinoma (ESCC) represents one of the leading causes of cancer… Expand
  • table 1
  • table 2
  • figure 4
Is this relevant?
1999
1999
Nonmuscle tropomyosin-4 requires coexpression with other low molecular weight isoforms for binding to thin filaments in cardiomyocytes.
Vertebrate tropomyosins (TMs) are expressed from four genes, and at least 18 distinct isoforms are generated via a complex… Expand
Is this relevant?
1987
1987
Characterization of a cDNA defining a gene family encoding TM30p1, a human fibroblast tropomyosin.
We have isolated a cDNA that contains the complete coding sequence of a 3.0 X 10(3) base human fibroblast mRNA together with a… Expand
Is this relevant?