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Triptans

Derivatives of TRYPTAMINES that are SEROTONIN RECEPTOR AGONISTS acting at 5-HT1 RECEPTORS. Some are used to treat MIGRAINE DISORDERS.
National Institutes of Health

Papers overview

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Review
2011
Review
2011
Over the years, there has been a considerable amount of controversy as to whether the vascular component of migraine pain arises… 
2010
2010
Objective.— To investigate the role of 5‐HT7 receptors on the release of calcitonin gene‐related peptide (CGRP) in an animal… 
Highly Cited
2009
Highly Cited
2009
Objective.— This study evaluated the pharmacokinetic and tolerability profiles of Zelrix™ (NuPathe Inc., Conshohocken, PA, USA… 
2008
2008
Objectives.— To analyze the demographics, diagnosis, and treatment patterns in patients with headache‐seeking treatment in one of… 
2005
2005
Objective.—To evaluate the impact of treatment with rizatriptan 10 mg on jobs and quality of life of patients with migraine. 
Review
2005
Review
2005
Many women experience headaches, including migraine, in association with their menstrual cycles. Although definitions vary… 
Review
2001
Review
2001
T HERE ARE 4 triptans currently available in theUnitedStates, and 3moreareexpectedto be approved by the Food and Drug…