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Triptans

Derivatives of TRYPTAMINES that are SEROTONIN RECEPTOR AGONISTS acting at 5-HT1 RECEPTORS. Some are used to treat MIGRAINE DISORDERS.
National Institutes of Health

Papers overview

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Highly Cited
2012
Highly Cited
2012
Objective.— To evaluate the efficacy of telcagepant in patients with migraine and coronary artery disease. 
Review
2011
Review
2011
Over the years, there has been a considerable amount of controversy as to whether the vascular component of migraine pain arises… 
2010
2010
Objective.— To investigate the role of 5‐HT7 receptors on the release of calcitonin gene‐related peptide (CGRP) in an animal… 
Highly Cited
2009
Highly Cited
2009
Objective.— This study evaluated the pharmacokinetic and tolerability profiles of Zelrix™ (NuPathe Inc., Conshohocken, PA, USA… 
2008
2008
Objectives.— To analyze the demographics, diagnosis, and treatment patterns in patients with headache‐seeking treatment in one of… 
2003
2003
Objective.—To compare the efficacy of a fixed combination of indomethacin, prochlorperazine, and caffeine suppositories with… 
Review
2001
Review
2001
T HERE ARE 4 triptans currently available in theUnitedStates, and 3moreareexpectedto be approved by the Food and Drug…