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Triptans

Derivatives of TRYPTAMINES that are SEROTONIN RECEPTOR AGONISTS acting at 5-HT1 RECEPTORS. Some are used to treat MIGRAINE DISORDERS.
National Institutes of Health

Papers overview

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Review
2019
Review
2019
ABSTRACT Introduction: Migraine is the most common of all neurological disorders. A breakthrough in migraine treatment emerged in… Expand
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Review
2019
Review
2019
  • D. Dodick
  • Cephalalgia : an international journal of…
  • 2019
  • Corpus ID: 58655789
Background: Monoclonal antibodies that target calcitonin gene-related peptide or the canonical calcitonin gene-related peptide… Expand
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Review
2018
Review
2018
BackgroundThe MAST Study is a longitudinal, cross-sectional survey study of US adults with migraine. These analyses were… Expand
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Review
2018
Review
2018
BackgroundMigraine is prevalent everywhere, and disabling. It is also neglected: consequently, it is under-diagnosed and… Expand
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Highly Cited
2009
Highly Cited
2009
Background:  Migraine is one of the most frequent disabling neurological conditions with a major impact on the patients’ quality… Expand
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Highly Cited
2004
Highly Cited
2004
For many migraine patients, triptan therapy provides complete pain relief in some attacks but not in others. Here, we tested… Expand
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Highly Cited
2004
Highly Cited
2004
Background: Triptans are widely used to treat migraine but have been associated with stroke, myocardial infarction (MI), and… Expand
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Highly Cited
2004
Highly Cited
2004
We have shown that the development of cutaneous allodynia (exaggerated skin sensitivity) during migraine is detrimental to the… Expand
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Review
2004
Review
2004
Background.—Health care providers frequently cite concerns about cardiovascular safety of the triptans as a barrier to their use… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND The triptans, selective serotonin 5-HT(1B/1D) agonists, are very effective acute migraine drugs with a well- developed… Expand
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