Trimebutine

Known as: Benzoic acid, 3,4,5-trimethoxy-, 2-(dimethylamino)-2-phenylbutyl ester, Trimebutine [Chemical/Ingredient] 
Proposed spasmolytic with possible local anesthetic action used in gastrointestinal disorders.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1971-2016
051019712016

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
BACKGROUND & AIMS The treatment of irritable bowel syndrome (IBS), characterized by abdominal pain and bloating, is empirical and… (More)
Is this relevant?
2002
2002
BACKGROUND/AIMS GERD (gastroesophageal reflux disease) occurs in 25-51% of IBS (irritable bowel syndrome) patients. Trimebutine… (More)
Is this relevant?
2002
2002
The objectives of this study were to produce acid soluble, polyvinylacetal diethylaminoacetate (AEA) microspheres containing… (More)
Is this relevant?
1999
1999
Trimebutine [2-dimethylamino-2-phenylbutyl-3,4,5-trimethoxybenzoate hydrogen maleate (TMB)] has been demonstrated to be active… (More)
  • figure 1
  • figure 2
  • figure 3
  • figure 5
  • figure 4
Is this relevant?
1997
1997
BACKGROUND Anal sphincter spasm may aggravate pain after haemorrhoidectomy. The aims of this study were to investigate whether a… (More)
Is this relevant?
1991
1991
The pharmacological profile of bethanechol (CAS 674-38-4), metoclopramide (CAS 364-62-5), trimebutine (CAS 39133-31-8) and… (More)
Is this relevant?
1989
1989
Trimebutine maleate (I), (+-)-2-dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoate hydrogen maleate, and a deuterium-labeled… (More)
Is this relevant?
1987
1987
Affinities of trimebutine (TMB) and N-desmethyl trimebutine (NDTMB) for mu, delta and kappa opioid receptor subtypes have been… (More)
Is this relevant?
1979
1979
Twenty adult Indian patients suffering from the spastic form of irritable colon, i.e. abdominal pain and constipation, were given… (More)
Is this relevant?
1978
1978
  • K Lüttecke
  • The Journal of international medical research
  • 1978
In a double-blind crossover trial of three days duration on each drug, trimebutine in a dose of 200 mg three times daily was… (More)
Is this relevant?