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Trihexyphenidyl

Known as: Trihexyphenidylum, (RS)-1-cyclohexyl-1-phenyl-3-(1-piperidyl)propan-1-ol, 1-Piperidinepropanol, alpha-cyclohexyl-alpha-phenyl- 
One of the centrally acting MUSCARINIC ANTAGONISTS used for treatment of PARKINSONIAN DISORDERS and drug-induced extrapyramidal movement disorders… 
National Institutes of Health

Related topics

Related topics

32 relations
Abnormalities, Drug-InducedAngle Closure GlaucomaBladder neck obstructionEsophageal Achalasia

Broader (6)

AlcoholsAminesAntiparkinson AgentsAntispasmodics

Narrower (7)

ArtaneCyclodolParkinaneParkopan

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2003
Highly Cited
2003
Caffeine and muscarinic antagonists act in synergy to inhibit haloperidol-induced catalepsy
Highly Cited
1997
Highly Cited
1997
The action of acetylcholine and other drugs on the efflux of potassium and rubidium from smooth muscle of the guinea‐pig intestine
1 . A method is described for measuring continuously the efflux of potassium or rubidium from smooth muscle of the guinea‐pig. 2… 
1991
1991
Efficacy evaluation of physostigmine and anticholinergic adjuncts as a pretreatment for nerve agent intoxication.
1989
1989
Schizophrenic psychosis associated with benzhexol (artane) therapy.
3 Dolich BH, Aiache AE. Drug induced Coma: A cause of Crush Syndrome and Ischemic Contracture. J Trawna 1973;13:223-8. 4 Shields… 
1989
1989
Focal Changes in the Globi Pallidi Associated with Neurological Dysfunction in Methylmalonic Acidaemia
Neurological abnormalities are common in patients with organic acidaemias and sometimes these are distinctive. Lesions in various… 
Highly Cited
1988
Highly Cited
1988
Muscarinic M1, M2 receptor binding. Relationship with functional efficacy.
1984
1984
Tolerance to an anticholinergic agent is paralleled by increased binding to muscarinic receptors in rat brain and increased behavioral response to a centrally active cholinomimetic.
Highly Cited
1982
Highly Cited
1982
Anti-Cholinergic Drugs and Memory: the Effects of Benzhexol on Memory in a Group of Geriatric Patients
Summary A double blind trial on the effects of 2 mg of benzhexol on memory was performed on thirteen elderly subjects without… 
Highly Cited
1981
Highly Cited
1981
Muscarinic cholinergic binding sites on intact human lymphocytes.
1973
1973
Antimuscarinic drugs--effect on brain acetylcholine and tremors in rats.
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