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Transient Receptor Potential Cation Channel Subfamily V Member 6

Known as: CaT1, CaT-like, Epithelial Calcium Channel 2 
A protein found in cell membranes that moves calcium into cells. Levels of transient receptor potential cation channel, subfamily V, member 6 are… 
National Institutes of Health

Related topics

Related topics

15 relations
Calcium SignalingCellular MembraneGastrointestinal tract structureHomo sapiens

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Crystal Structure of the Epithelial Calcium Channel TRPV6
Precise regulation of calcium homeostasis is essential for many physiological functions. The Ca2+-selective transient receptor… 
Highly Cited
2012
Highly Cited
2012
Villin promoter‐mediated transgenic expression of transient receptor potential cation channel, subfamily V, member 6 (TRPV6) increases intestinal calcium absorption in wild‐type and vitamin D…
Transient receptor potential cation channel, subfamily V, member 6 (TRPV6) is an apical membrane calcium (Ca) channel in the… 
Highly Cited
2012
Highly Cited
2012
Distinguishing between Selective Sweeps from Standing Variation and from a De Novo Mutation
An outstanding question in human genetics has been the degree to which adaptation occurs from standing genetic variation or from… 
Highly Cited
2009
Highly Cited
2009
Intestinal vitamin D receptor is required for normal calcium and bone metabolism in mice.
BACKGROUND & AIMS Vitamin D receptor (VDR)-knockout mice develop severe hypocalcemia and rickets, accompanied by disruption of… 
Highly Cited
2007
Highly Cited
2007
Vitamin D Receptor: Key Roles in Bone Mineral Pathophysiology, Molecular Mechanism of Action, and Novel Nutritional Ligands
The vitamin D hormone, 1,25‐dihydroxyvitamin D3 [1,25(OH)2D3], binds with high affinity to the nuclear vitamin D receptor (VDR… 
Highly Cited
2004
Highly Cited
2004
Activation of cAMP Response Element-Mediated Gene Expression by Regulated Nuclear Transport of TORC Proteins
Review
2003
Review
2003
Mechanisms of intestinal calcium absorption
Calcium is absorbed in the mammalian small intestine by two general mechanisms: a transcellular active transport process, located… 
Highly Cited
2003
Highly Cited
2003
Regulation of the epithelial Ca2+ channels in small intestine as studied by quantitative mRNA detection.
The epithelial Ca2+ channels TRPV5 and TRPV6 are localized to the brush border membrane of intestinal cells and constitute the… 
Highly Cited
2001
Highly Cited
2001
Function and expression of the epithelial Ca2+ channel family: comparison of mammalian ECaC1 and 2
1 The epithelial Ca2+ channel (ECaC) family represents a unique group of Ca2+‐selective channels that share limited homology to… 
Highly Cited
2001
Highly Cited
2001
Competitive regulation of CaT-like-mediated Ca2+ entry by protein kinase C and calmodulin
A finely tuned Ca2+ signaling system is essential for cells to transduce extracellular stimuli, to regulate growth, and to… 
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