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Transducin

Known as: G Protein, Inhibitory Gt, Transducin G-Protein Gt, Transducin G-Protein (Gt) 
A heterotrimeric GTP-binding protein that mediates the light activation signal from photolyzed rhodopsin to cyclic GMP phosphodiesterase and is… 
National Institutes of Health

Related topics

Related topics

12 relations

Broader (1)

GTP-Binding Proteins
In BloodProcess of secretionagonistsantagonists & inhibitors

Narrower (3)

alpha-Transducinbeta-Transducingamma-Transducin

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2000
2000
Coupling between the N- and C-terminal domains influences transducin-alpha intrinsic GDP/GTP exchange.
The N-terminal regions of the heterotrimeric G-protein alpha-subunits represent one of the major Gbetagamma contact sites and… 
1996
1996
High affinity interactions of GTPgammaS with the heterotrimeric G protein, transducin. Evidence at high and low protein concentrations.
A well known difference in nucleotide binding characteristics between heterotrimeric G proteins and small GTP binding proteins of… 
1996
1996
Uncoupling of GTP Binding from Target Stimulation by a Single Mutation in the Transducin α Subunit
Glutamic acid-203 of the alpha subunit of transducin (αT) resides within a domain that undergoes a guanosine triphosphate (GTP… 
1994
1994
Structure and function in rhodopsin: covalent crosslinking of the rhodopsin (metarhodopsin II)-transducin complex--the rhodopsin cytoplasmic face links to the transducin alpha subunit.
We prepared rhodopsin mutants that contained a single reactive cysteine residue per rhodopsin molecule at position 65, 140, 240… 
1993
1993
Prenyl modification of guanine nucleotide regulatory protein gamma 2 subunits is not required for interaction with the transducin alpha subunit or rhodopsin.
Guanine nucleotide-binding regulatory protein (G protein) beta gamma dimers that were active in reconstitution assays were… 
1990
1990
Displacement of rhodopsin by GDP from three-loop interaction with transducin depends critically on the diphosphate beta-position.
We have studied the effect of GDP and its analog guanyl-5'-yl thiophosphate (GDP beta S) on the interaction between rhodopsin and… 
1986
1986
Interaction of retinal transducin with guanosine triphosphate analogues: specificity of the gamma-phosphate binding region.
The interaction of six hydrolysis-resistant analogues of GTP with transducin, the signal-coupling protein in vertebrate… 
1986
1986
C-terminal peptides of rhodopsin. Determination of the optimum sequence for recognition of retinal transducin.
In vertebrate retinal rod outer segments, transducin, a guanine-nucleotide-binding protein, mediates signal coupling between… 
1985
1985
Pertussis toxin inhibition of chemotaxis and the ADP-ribosylation of a membrane protein in a human-mouse hybrid cell line.
When WBC264-9C cells are preincubated with pertussis toxin, chemotaxis is inhibited and ADP-ribosylation of a membrane protein… 
Highly Cited
1983
Highly Cited
1983
Transducin and the cyclic GMP phosphodiesterase: amplifier proteins in vision.
Our experiments have delineated the flow of information in the cyclic nucleotide cascade of vision of ROS. A single, photoexcited… 
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