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Transcription Initiation Site

Known as: Transcription Start Sites, Site, Transcription Initiation, Sites, Transcription Initiation 
The first nucleotide of a transcribed DNA sequence where RNA polymerase (DNA-DIRECTED RNA POLYMERASE) begins synthesizing the RNA transcript.
National Institutes of Health

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Highly Cited
2012
Highly Cited
2012
The vast non-coding portion of the human genome is full of functional elements and disease-causing regulatory variants. The… Expand
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Highly Cited
2008
Highly Cited
2008
The positioning of nucleosomes with respect to DNA plays an important role in regulating transcription. However, nucleosome… Expand
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Highly Cited
2007
Highly Cited
2007
We report the generation and analysis of functional data from multiple, diverse experiments performed on a targeted 1% of the… Expand
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Highly Cited
2007
Highly Cited
2007
Certain G-rich DNA sequences readily form four-stranded structures called G-quadruplexes. These sequence motifs are located in… Expand
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Highly Cited
2006
Highly Cited
2006
Mammalian promoters can be separated into two classes, conserved TATA box–enriched promoters, which initiate at a well-defined… Expand
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Highly Cited
2006
Highly Cited
2006
Lysine methylation of histones is recognized as an important component of an epigenetic indexing system demarcating… Expand
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Highly Cited
2005
Highly Cited
2005
Estrogen plays an essential physiologic role in reproduction and a pathologic one in breast cancer. The completion of the human… Expand
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Highly Cited
1997
Highly Cited
1997
PPARγ is a member of the PPAR subfamily of nuclear receptors. In this work, the structure of the human PPARγ cDNA and gene was… Expand
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Highly Cited
1987
Highly Cited
1987
Although vertebrate DNA is generally depleted in the dinucleotide CpG, it has recently been shown that some vertebrate genes… Expand
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Highly Cited
1983
Highly Cited
1983
Fractionation of HeLa cell extracts reveals the presence of a promoter-specific transcription factor, Sp 1, which activates a… Expand
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