Transcription Initiation Site

Known as: Transcription Start Sites, Site, Transcription Initiation, Sites, Transcription Initiation 
The first nucleotide of a transcribed DNA sequence where RNA polymerase (DNA-DIRECTED RNA POLYMERASE) begins synthesizing the RNA transcript.
National Institutes of Health

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Highly Cited
2013
Highly Cited
2013
Structural visualization of key steps in human transcription initiation
Eukaryotic transcription initiation requires the assembly of general transcription factors into a pre-initiation complex that… (More)
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Highly Cited
2011
Highly Cited
2011
TET1 and hydroxymethylcytosine in transcription and DNA methylation fidelity
Enzymes catalysing the methylation of the 5-position of cytosine (mC) have essential roles in regulating gene expression and… (More)
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Highly Cited
2009
Highly Cited
2009
Transcription Initiation Activity Sets Replication Origin Efficiency in Mammalian Cells
Genomic mapping of DNA replication origins (ORIs) in mammals provides a powerful means for understanding the regulatory… (More)
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Highly Cited
2009
Highly Cited
2009
Tiny RNAs associated with transcription start sites in animals
It has been reported that relatively short RNAs of heterogeneous sizes are derived from sequences near the promoters of… (More)
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Highly Cited
2007
Highly Cited
2007
A code for transcription initiation in mammalian genomes.
Genome-wide detection of transcription start sites (TSSs) has revealed that RNA Polymerase II transcription initiates at millions… (More)
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Highly Cited
2004
Highly Cited
2004
Retroviral DNA Integration: ASLV, HIV, and MLV Show Distinct Target Site Preferences
The completion of the human genome sequence has made possible genome-wide studies of retroviral DNA integration. Here we report… (More)
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Highly Cited
2004
Highly Cited
2004
Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome.
Almost 1-2% of the human genome is located within 500 bp of either side of a transcription initiation site, whereas a far larger… (More)
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Highly Cited
2002
Highly Cited
2002
A transcription factor response element for gene expression during circadian night
Mammalian circadian clocks consist of complex integrated feedback loops that cannot be elucidated without comprehensive… (More)
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Highly Cited
1998
Highly Cited
1998
Regulation of vascular endothelial growth factor (VEGF) expression is mediated by internal initiation of translation and alternative initiation of transcription
Vascular Endothelial Growth Factor (VEGF) is a very potent angiogenic agent that has a central role in normal physiological… (More)
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Highly Cited
1983
Highly Cited
1983
The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter
Fractionation of HeLa cell extracts reveals the presence of a promoter-specific transcription factor, Sp 1, which activates a… (More)
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