Transcription Factor 7-Like 2

Known as: T Cell Transcription Factor 4, HMG Box Transcription Factor 4, Transcription Factor 7-Like 2 Protein 
A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN… (More)

Topic mentions per year

Topic mentions per year

1999-2017
05010019992017

Papers overview

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Highly Cited
2008
Highly Cited
2008
BACKGROUND Type 2 diabetes mellitus is thought to develop from an interaction between environmental and genetic factors. We… (More)
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Highly Cited
2008
Highly Cited
2008
OBJECTIVE Type 2 diabetes is characterized by impaired insulin secretion in response to increased metabolic demand. This defect… (More)
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Highly Cited
2007
Highly Cited
2007
Polymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes and reduced insulin… (More)
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Highly Cited
2007
Highly Cited
2007
We conducted a genome-wide association study for type 2 diabetes (T2D) in Icelandic cases and controls, and we found that a… (More)
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Highly Cited
2007
Highly Cited
2007
Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has been a formidable challenge… (More)
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Highly Cited
2006
Highly Cited
2006
We have previously reported suggestive linkage of type 2 diabetes mellitus to chromosome 10q. We genotyped 228 microsatellite… (More)
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Highly Cited
2006
Highly Cited
2006
Transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Genetic variants within TCF7L2 on chromosome 10q… (More)
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Highly Cited
2006
Highly Cited
2006
Transcription factor 7-like 2 (TCF7L2) regulates genes involved in cell proliferation and differentiation. The TCF7L2 gene is… (More)
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2006
2006
Recently, the transcription factor 7-like 2 (TCF7L2) gene on chromosome 10q25.2 has been linked with type 2 diabetes among… (More)
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Highly Cited
2006
Highly Cited
2006
Recently, the transcription factor 7-like 2 (TCF7L2) gene has been associated with type 2 diabetes in subjects of European origin… (More)
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