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Transcription Factor 7-Like 2

Known as: T Cell Transcription Factor 4, HMG Box Transcription Factor 4, Transcription Factor 7-Like 2 Protein 
A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN… 
National Institutes of Health

Related topics

Related topics

20 relations
DNA-Binding ProteinsGenes, RegulatorIn BloodMelanogenesis Pathway

Papers overview

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2016
2016
Polymorphisms in the Fat Mass and Obesity Associated ( FTO ) and Transcription factor 7-like 2 ( TCF 7 L 2 ) genes in Euro-Brazilian individuals with type 2 diabetes
  • 2016
  • Corpus ID: 52214790
Type 2 diabetes (T2D) is a condition that causes a substantial public health burden worldwide. In recent years, several genetic… 
2016
2016
The transcriptional factor Tcf-4 contains different binding sites for β-catenin and plakoglobin.
(cid:1) -Catenin and plakoglobin are two related armadillo proteins necessary for the establishment of adhesion junctions and… 
2015
2015
IKK b Enforces a LIN 28 B / TCF 7 L 2 Positive Feedback Loop That Promotes Cancer Cell Stemness and Metastasis
Considerable evidence suggests that proinflammatory pathways drive self-renewal of cancer stem-like cells (CSC), but the… 
2014
2014
Molecular Heterogeneity of Type 2 Diabetes Mellitus in Mexican Populationand its Impact of the Public Health on Policies in Primary Care
Type 2 diabetes mellitus is a complex disease and a global health problem; hence the first level of health care should handle the… 
2014
2014
Does TCF7L2 polymorphisms increase the risk of gestational diabetes mellitus in South Indian population
Review
2014
Review
2014
An insight into diabesity – A short review.
Diabetes and obesity are both increasing dramatically in the United States of America and other parts of the world. One third of… 
2012
2012
Association of 15 candidate genes with meat quality traits in Czech Large White pigs
Meat quality traits are a crucial factor in efficient pork production. In this work, we studied the influence of fifteen genes… 
2009
2009
The inhibitory effect of recent type 2 diabetes risk loci on insulin secretion is modulated by insulin sensitivity.
CONTEXT/OBJECTIVE Recently novel type 2 diabetes risk loci were identified and reported to associate with beta-cell dysfunction… 
2009
2009
Molecular SNPlotypes™ with common alleles reflects expression profile in Diabetes Mellitus Type 2
Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex and a heterogeneous group of metabolic conditions characterized by… 
2006
2006
No major contribution of TCF7L2 sequence variants to maturity onset of diabetes of the young (MODY) or neonatal diabetes mellitus in French white subjects
To the Editor: Maturity onset diabetes of the young (MODY), and permanent and transient neonatal diabetes mellitus (NDM), are the…