Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Transcription Factor 7-Like 2

Known as: T Cell Transcription Factor 4, HMG Box Transcription Factor 4, Transcription Factor 7-Like 2 Protein 
A transcription factor that takes part in WNT signaling pathway. The activity of the protein is regulated via its interaction with BETA CATENIN… Expand
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Identifying and understanding changes in cancer genomes is essential for the development of targeted therapeutics. Here we… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
Is this relevant?
Highly Cited
2010
Highly Cited
2010
Glucose levels 2 h after an oral glucose challenge are a clinical measure of glucose tolerance used in the diagnosis of type 2… Expand
  • figure 1
  • figure 2
  • figure 3
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Identifying the genetic variants that increase the risk of type 2 diabetes (T2D) in humans has been a formidable challenge… Expand
Is this relevant?
Highly Cited
2007
Highly Cited
2007
Aims/hypothesisPolymorphisms in the transcription factor 7-like 2 (TCF7L2) gene are associated with type 2 diabetes and reduced… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
  • table 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
We have previously reported suggestive linkage of type 2 diabetes mellitus to chromosome 10q. We genotyped 228 microsatellite… Expand
  • table 1
  • figure 1
  • table 2
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Transcription factor 7-like 2 (TCF7L2) regulates genes involved in cell proliferation and differentiation. The TCF7L2 gene is… Expand
  • figure 1
  • table 1
  • table 2
  • table 3
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Transcription factor 7-like 2 (TCF7L2) is part of the Wnt signaling pathway. Genetic variants within TCF7L2 on chromosome 10q… Expand
  • table 1
  • table 2
  • table 3
  • table 4
Is this relevant?
Highly Cited
2006
Highly Cited
2006
Recently, the transcription factor 7-like 2 (TCF7L2) gene has been associated with type 2 diabetes in subjects of European origin… Expand
  • table 1
  • table 2
  • figure 1
  • figure 2
Is this relevant?
Highly Cited
1998
Highly Cited
1998
Mutations of the genes encoding APC or ß-catenin in colon carcinoma induce the constitutive formation of nuclear ß-catenin/Tcf-4… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5
Is this relevant?
Highly Cited
1997
Highly Cited
1997
The adenomatous polyposis coli (APC) tumor suppressor protein binds to β-catenin, a protein recently shown to interact with Tcf… Expand
Is this relevant?