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Transcobalamin

Known as: Vitamin B12-Binding Proteins, Proteins, Cobalamin-Binding, Cobalamin-Binding Proteins 
A group of carrier proteins which bind with VITAMIN B12 in the BLOOD and aid in its transport. Transcobalamin I migrates electrophoretically as a… 
National Institutes of Health

Related topics

Related topics

20 relations
Apo-transcobalamin I:SCnc:Pt:Ser:QnApo-transcobalamin II:SCnc:Pt:Ser:QnHolo-transcobalamin II:SCnc:Pt:Ser:QnProcess of secretion

Narrower (6)

Holo-Transcobalamin IIR-BinderTranscobalamin ITranscobalamin I Deficiency

Broader (1)

Vitamin B 12

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2008
2008
Polymorphisms in genes related to folate and cobalamin metabolism and the associations with complex birth defects
To investigate the associations between biomarkers and genetic variants involved in homocysteine metabolism and the risk of… 
1994
1994
Nonsense mutations in human transcobalamin II deficiency.
Reverse transcription-polymerase chain reaction has been used to amplify, clone and sequence transcobalamin II (TC II) cDNA from… 
1992
1992
The neurologic aspects of transcobalamin II deficiency
Summary. Thirty‐four symptomatic cases of inherited transcobalamin II (TCII) deficiency were analysed in order to determine the… 
Highly Cited
1991
Highly Cited
1991
The cDNA sequence and the deduced amino acid sequence of human transcobalamin II show homology with rat intrinsic factor and human transcobalamin I.
The cellular uptake of cobalamin (Cbl, vitamin B12) is mediated by transcobalamin II (TCII), a plasma protein that binds Cbl and… 
1991
1991
Lysosomal cobalamin accumulation in fibroblasts from a patient with an inborn error of cobalamin metabolism (cblF complementation group): visualization by electron microscope radioautography.
1981
1981
Cobalamin binding and uptake in vitro in the human central nervous system.
Little information exists about the CNS transport of cobalamin. Therefore we undertook to characterize the cobalamin-binding… 
1980
1980
Studies of a patient with megaloblastic anemia and an abnormal transcobalamin II.
TRANSCOBALAMIN II, a 38,000-dalton plasma protein, has a single binding site for cobalamin (vitamin B12) and functions as the… 
Review
1978
Review
1978
Detection of genetic variation with radioactive ligands. III. genetic polymorphism of transcobalamin II in human plasma.
We detected genetically determined, electrophoretic variants of vitamin B12 binding proteins, most probably transcobalamin II, in… 
1975
1975
Transport of vitamin B12 into mouse leukemia cells.
Highly Cited
1972
Highly Cited
1972
Isolation of vitamin B12-binding proteins using affinity chromatography. 3. Purification and properties of human plasma transcobalamin II.
Abstract Transcobalamin II has been isolated from Cohn Fraction III derived from 1,400 liters of pooled human plasma, using… 
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