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Tramadol

Known as: Cyclohexanol, 2-((dimethylamino)methyl)-1-(3-methoxyphenyl)-, cis-(+-)-, Tramadol [Chemical/Ingredient], (+)-trans-2-(Dimethylaminomethyl)-1-(m-methoxyphenyl)cyclohexanol 
A synthetic codeine analogue, Tramadol has central analgesic properties with effects similar to opioids, such as morphine and codeine, acting on… Expand
National Institutes of Health

Papers overview

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Review
2012
Review
2012
To update the American College of Rheumatology (ACR) 2000 recommendations for hip and knee osteoarthritis (OA) and develop new… Expand
Review
2010
Review
2010
Background and objectives:  This second European Federation of Neurological Societies Task Force aimed at updating the existing… Expand
Review
2006
Review
2006
BACKGROUND Peripheral neuropathic pains often include symptoms such as burning or shooting sensations, abnormal sensitivity to… Expand
Review
2004
Review
2004
Tramadol, a centrally acting analgesic structurally related to codeine and morphine, consists of two enantiomers, both of which… Expand
Review
2000
Review
2000
UNLABELLED Tramadol is a synthetic, centrally acting analgesic agent with 2 distinct, synergistic mechanisms of action, acting as… Expand
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Highly Cited
1998
Highly Cited
1998
Objective The objective of this study was to evaluate the efficacy and safety of tramadol in treating the pain of diabetic… Expand
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Highly Cited
1996
Highly Cited
1996
Tramadol inhibits norepinephrine reuptake, stimulates serotonin release, and acts with μ‐opioid receptors by way of its… Expand
Review
1993
Review
1993
Tramadol is a centrally acting analgesic which possesses opioid agonist properties and activates monoaminergic spinal inhibition… Expand
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Highly Cited
1993
Highly Cited
1993
The explanation for the co-existence of opioid and nonopioid components of tramadol-induced antinociception appears to be related… Expand
Highly Cited
1992
Highly Cited
1992
Two independent clinical trials were conducted simultaneously. In one, tramadol and pethidine were compared in 30 patients by… Expand