FAQ

Tolnaftate

Known as: Tolnaphthate, O-2-Naphthyl m,N-dimethylthiocarbanilate, Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester 
A thiocarbamate derivative with either fungicidal or fungistatic property. Tolnaftate is a selective, reversible and non-competitive inhibitor of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2018
051019642018

Related topics

Related topics

35 relations

Broader (1)

Antifungal Agents

Narrower (12)

ChinofunginClarusNP-27Tinactin
(More)
HypersensitivityIn BloodOnychomycosisScalp Dermatoses
(More)

Related mentions per year

Related mentions per year

1936-2018
19401960198020002020
Tolnaftate
Hypersensitivity
Antifungal Agents
In Blood
chemical synthesis
Onychomycosis

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Study of tolnaftate release from fatty acids containing ointment and penetration into human skin ex vivo.
Five fatty acids (oleic, linoleic, myristic, lauric and capric) were incorporated in 10% (w/w) into ointment formulation and… (More)
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2010
2010
Assay of tolnaftate in human skin samples after in vitro penetration studies using high performance liquid chromatography.
Abstract: Tolnaftate, an antifungal of thiocarbamate class, is used topically in 1% formulations. Its penetration into skin… (More)
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2004
2004
Tolnaftate spray treatment during pregnancy.
Teratogenic studies of tolnaftate, an antifungal agent, in humans have not been published. The population-based data set of the… (More)
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2003
2003
Comparison of in vitro activities of 17 antifungal drugs against a panel of 20 dermatophytes by using a microdilution assay.
The in vitro activities of 17 antifungal drugs against a panel of 20 dermatophytes comprising 6 different species were determined… (More)
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Highly Cited
2003
Highly Cited
2003
Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine.
The in vitro antifungal susceptibilities of six clinical Trichophyton rubrum isolates obtained sequentially from a single… (More)
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2001
2001
[Therapeutic efficacy of a topical tolnaftate preparation in guinea pig model of tinea pedis].
The therapeutic efficacy of a topical antifungal ointment containing 2% tolnaftate was studied in a guinea pig model of tinea… (More)
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1998
1998
Enhancing effect of N-acetyl-l-cysteine or 2-mercaptoethanol on the in vitro permeation of 5-fluorouracil or tolnaftate through the human nail plate.
The enhancing effects of various vehicles on the in vitro permeation of a hydrophilic model drug, 5-fluorouracil (5-FU), or a… (More)
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1991
1991
Studies on the mode of action of tolnaftate in Microsporum gypseum.
Studies were performed on the mode of action of tolnaftate and resistance to this drug in Microsporum gypseum. Cells grown in the… (More)
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1986
1986
The mode of antifungal action of tolnaftate.
The anti-dermatophyte agent tolnaftate was compared with the allylamine antifungal compounds naftifine and terbinafine… (More)
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1986
1986
Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate.
The thiocarbamate antimycotics tolnaftate and tolciclate blocked sterol biosynthesis in fungal cells and cell extracts, with… (More)
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