Tolnaftate

Known as: Tolnaphthate, O-2-Naphthyl m,N-dimethylthiocarbanilate, Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester 
A thiocarbamate derivative with either fungicidal or fungistatic property. Tolnaftate is a selective, reversible and non-competitive inhibitor of… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1964-2018
051019642018

Papers overview

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2011
2011
Five fatty acids (oleic, linoleic, myristic, lauric and capric) were incorporated in 10% (w/w) into ointment formulation and… (More)
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2010
2010
Abstract: Tolnaftate, an antifungal of thiocarbamate class, is used topically in 1% formulations. Its penetration into skin… (More)
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2004
2004
Teratogenic studies of tolnaftate, an antifungal agent, in humans have not been published. The population-based data set of the… (More)
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2003
2003
The in vitro activities of 17 antifungal drugs against a panel of 20 dermatophytes comprising 6 different species were determined… (More)
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Highly Cited
2003
Highly Cited
2003
The in vitro antifungal susceptibilities of six clinical Trichophyton rubrum isolates obtained sequentially from a single… (More)
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2001
2001
The therapeutic efficacy of a topical antifungal ointment containing 2% tolnaftate was studied in a guinea pig model of tinea… (More)
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1998
1998
The enhancing effects of various vehicles on the in vitro permeation of a hydrophilic model drug, 5-fluorouracil (5-FU), or a… (More)
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1991
1991
Studies were performed on the mode of action of tolnaftate and resistance to this drug in Microsporum gypseum. Cells grown in the… (More)
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1986
1986
The anti-dermatophyte agent tolnaftate was compared with the allylamine antifungal compounds naftifine and terbinafine… (More)
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1986
1986
The thiocarbamate antimycotics tolnaftate and tolciclate blocked sterol biosynthesis in fungal cells and cell extracts, with… (More)
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