Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

Tolnaftate

Known as: Tolnaphthate, O-2-Naphthyl m,N-dimethylthiocarbanilate, Methyl (3-methylphenyl)carbamothioic acid O-2-naphthalenyl ester 
A thiocarbamate derivative with either fungicidal or fungistatic property. Tolnaftate is a selective, reversible and non-competitive inhibitor of… Expand
National Institutes of Health

Related topics

Related topics

35 relations

Narrower (9)

ChloriseptFocusanMycocideNP-27
Expand
In BloodOnychomycosisTinea PedisTinea Versicolor
Expand

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Assay of tolnaftate in human skin samples after in vitro penetration studies using high performance liquid chromatography.
Abstract: Tolnaftate, an antifungal of thiocarbamate class, is used topically in 1% formulations. Its penetration into skin… Expand
  • figure 1
  • figure 2
  • figure 3
  • table 1
  • table 2
Is this relevant?
Review
2010
Review
2010
Otomycosis: Diagnosis and treatment.
Aspergillus and Candida spp are the most frequently isolated fungi in patients with otomycosis. The diagnosis of otitis externa… Expand
  • table 1
  • table 2
  • table 3
  • table 3
Is this relevant?
Review
2007
Review
2007
Topical treatments for fungal infections of the skin and nails of the foot.
BACKGROUND Fungal infections of the feet normally occur in the outermost layer of the skin (epidermis). The skin between the toes… Expand
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Clinical Trichophyton rubrum strain exhibiting primary resistance to terbinafine.
The in vitro antifungal susceptibilities of six clinical Trichophyton rubrum isolates obtained sequentially from a single… Expand
  • table 1
  • table 2
  • figure 1
  • table 3
Is this relevant?
Highly Cited
2003
Highly Cited
2003
Comparison of in vitro activities of 17 antifungal drugs against a panel of 20 dermatophytes by using a microdilution assay.
The in vitro activities of 17 antifungal drugs against a panel of 20 dermatophytes comprising 6 different species were determined… Expand
Is this relevant?
1998
1998
Enhancing effect of N-acetyl-l-cysteine or 2-mercaptoethanol on the in vitro permeation of 5-fluorouracil or tolnaftate through the human nail plate.
The enhancing effects of various vehicles on the in vitro permeation of a hydrophilic model drug, 5-fluorouracil (5-FU), or a… Expand
Is this relevant?
Highly Cited
1997
Highly Cited
1997
In-vitro permeability of the human nail and of a keratin membrane from bovine hooves: prediction of the penetration rate of antimycotics through the nail plate and their efficacy.
In contrast to the partition coefficient octanol/water the molecular size of penetrating drugs has a noticeable influence on the… Expand
Is this relevant?
1992
1992
Tea tree oil in the treatment of tinea pedis.
Tea tree oil (an essential oil derived primarily from the Australian native Melaleuca alternifolia) has been used as a topical… Expand
Is this relevant?
1986
1986
Ergosterol biosynthesis inhibition by the thiocarbamate antifungal agents tolnaftate and tolciclate.
The thiocarbamate antimycotics tolnaftate and tolciclate blocked sterol biosynthesis in fungal cells and cell extracts, with… Expand
  • table 1
  • figure 2
  • figure 1
  • table 2
  • table 3
Is this relevant?
1986
1986
The mode of antifungal action of tolnaftate.
The anti-dermatophyte agent tolnaftate was compared with the allylamine antifungal compounds naftifine and terbinafine… Expand
Is this relevant?
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy, Terms of Service, and Dataset License
ACCEPT & CONTINUE