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Tiludronate

Known as: (chloro-4-phenyl)thiomethylene biphosphonate, (chloro-4-phenyl)thiomethylene bisphosphonate 
 
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
IntroductionThe aim of this prospective, randomized, controlled, double-blind study was to evaluate the effects of tiludronate… Expand
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Review
2003
Review
2003
  • M. Rogers
  • Current pharmaceutical design
  • 2003
  • Corpus ID: 22525479
Bisphosphonates are currently the most important and effective class of anti-resorptive drugs available, but the exact molecular… Expand
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Highly Cited
2000
Highly Cited
2000
Bisphosphonates are the important class of antiresorptive drugs used in the treatment of metabolic bone diseases. Although their… Expand
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Review
1999
Review
1999
Bisphosphonates (BPs) used as inhibitors of bone resorption all contain two phosphonate groups attached to a single carbon atom… Expand
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Highly Cited
1997
Highly Cited
1997
Signaling pathways mediated by tyrosine phosphorylation and dephosphorylation have been reported to be involved in the regulation… Expand
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Highly Cited
1996
Highly Cited
1996
Although bisphosphonates have been shown to be potent inhibitors of osteoclast‐mediated bone resorption in vivo and in vitro and… Expand
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Highly Cited
1995
Highly Cited
1995
The mechanism of action of tiludronate [(4-chlorophenyl)-thiomethylene bisphosphonate] on osteoclastic bone resorption was… Expand
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Highly Cited
1995
Highly Cited
1995
OBJECTIVE To compare the efficacy and safety of tiludronate and etidronate at the same dosage (400 mg/day) for the treatment of… Expand
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Highly Cited
1995
Highly Cited
1995
Immobilization secondary to spinal cord injury is associated with a marked and rapid atrophy of trabecular bone (disuse… Expand
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Highly Cited
1989
Highly Cited
1989
76 healthy women, who had been menopausal for less than 96 months and who had never received any form of treatment to prevent… Expand
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