Tiludronate

IntroductionThe aim of this prospective, randomized, controlled, double-blind study was to evaluate the effects of tiludronate… Expand

Bisphosphonates are currently the most important and effective class of anti-resorptive drugs available, but the exact molecular… Expand

Bisphosphonates are the important class of antiresorptive drugs used in the treatment of metabolic bone diseases. Although their… Expand

Bisphosphonates (BPs) used as inhibitors of bone resorption all contain two phosphonate groups attached to a single carbon atom… Expand

Signaling pathways mediated by tyrosine phosphorylation and dephosphorylation have been reported to be involved in the regulation… Expand

Although bisphosphonates have been shown to be potent inhibitors of osteoclast‐mediated bone resorption in vivo and in vitro and… Expand

The mechanism of action of tiludronate [(4-chlorophenyl)-thiomethylene bisphosphonate] on osteoclastic bone resorption was… Expand

OBJECTIVE To compare the efficacy and safety of tiludronate and etidronate at the same dosage (400 mg/day) for the treatment of… Expand

Immobilization secondary to spinal cord injury is associated with a marked and rapid atrophy of trabecular bone (disuse… Expand

76 healthy women, who had been menopausal for less than 96 months and who had never received any form of treatment to prevent… Expand