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Tifacogin

 
National Institutes of Health

Papers overview

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2013
2013
SYSTEMIC ACTIVATION OF COAGUlation and thrombus formation in the microvasculature accompanies organ dysfunction and excess… Expand
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Highly Cited
2011
Highly Cited
2011
RATIONALE Severe community-acquired pneumonia (sCAP) is a leading cause of death worldwide. Adjunctive therapies for sCAP are… Expand
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2011
2011
Community-acquired pneumonia is the number one cause of severe sepsis and the seventh leading cause of death, with an estimated 1… Expand
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2011
2011
Endothelial cell injury during sepsis leads to activation of the coagulation process through tissue factor (TF), resulting in… Expand
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Review
2009
Review
2009
IntroductionThe purpose of this analysis was to determine the potential efficacy of recombinant human tissue factor pathway… Expand
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Review
2008
Review
2008
Patients with community-acquired pneumonia (CAP) in the hospital setting exhibit markedly abnormal levels of various biomarkers… Expand
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Review
2008
Review
2008
Despite effective antibiotic therapy, about one-third of patients admitted to an intensive care unit (ICU) with severe community… Expand
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Review
2005
Review
2005
Tifacogin is a recombinant tissue factor pathway inhibitor (rTFPI) under development by Pharmacia Corp. and Chiron as a potential… Expand
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Highly Cited
2003
Highly Cited
2003
CONTEXT The expression and release of tissue factor is a major trigger for the activation of coagulation in patients with sepsis… Expand
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