Tifacogin
National Institutes of Health
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SYSTEMIC ACTIVATION OF COAGUlation and thrombus formation in the microvasculature accompanies organ dysfunction and excess…
Community-acquired pneumonia is the number one cause of severe sepsis and the seventh leading cause of death, with an estimated 1…
Endothelial cell injury during sepsis leads to activation of the coagulation process through tissue factor (TF), resulting in…
Tifacogin does not appear to improve outcomes of patients with severe community-acquired pneumonia, according to a global study…
ZusammenfassungIm Gegensatz zu den beiden endogenen Antikoagulanzien Antithrombin und Tifacogin, die in 2 großen Studien an…
Tifacogin is a recombinant tissue factor pathway inhibitor (rTFPI) under development by Pharmacia Corp (formerly GD Searle) and…
The role of inflammation in cardiovascular disease and especially in thrombogenesis has become increasingly recognized as an…