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Thyrotropin, beta Subunit
Known as:
TSH beta
, Thyrotropin beta
, Thyrotropin, beta Chain
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The beta subunit of thyroid stimulating hormone, thyrotropin. It is a 112-amino acid glycopolypeptide of about 16 kD. Full biological activity of TSH…
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National Institutes of Health
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Related topics
Related topics
10 relations
In Blood
Process of secretion
TSHB gene
agonists
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Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1999
Highly Cited
1999
Ligand‐induced recruitment of a histone deacetylase in the negative‐feedback regulation of the thyrotropin β gene
Shigekazu Sasaki
,
Leslie A. Lesoon-Wood
,
+8 authors
K. Ozato
EMBO Journal
1999
Corpus ID: 16429678
We have investigated ligand‐dependent negative regulation of the thyroid‐stimulating hormone β (TSHβ) gene. Thyroid hormone (T3…
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Highly Cited
1999
Highly Cited
1999
Central hypothyroidism associated with retinoid X receptor-selective ligands.
S. Sherman
,
J. Gopal
,
+4 authors
M. Duvic
New England Journal of Medicine
1999
Corpus ID: 11090928
BACKGROUND The occurrence of symptomatic central hypothyroidism (characterized by low serum thyrotropin and thyroxine…
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Highly Cited
1996
Highly Cited
1996
A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain
Myung K. Kim
,
Leslie A. Lesoon-Wood
,
Bruce D. Weintraub
,
Jay H. Chung
Molecular and Cellular Biology
1996
Corpus ID: 7363924
Expression of the human thyrotropin beta (hTSHbeta) gene is restricted to thyrotrophs, at least in part, by silencing. Using…
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Highly Cited
1994
Highly Cited
1994
Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis.
G. A. C. V. Haasteren
,
M. V. D. Meer
,
+7 authors
W. J. Greef
Endocrinology
1994
Corpus ID: 20643648
The cytokines interleukin-1 (IL-1) and IL-6 are thought to be important mediators in the suppression of thyroid function during…
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Highly Cited
1993
Highly Cited
1993
Expression of the Xenopus laevis prolactin and thyrotropin genes during metamorphosis.
Leonard Buckbinder
,
Donald D. Brown
Proceedings of the National Academy of Sciences…
1993
Corpus ID: 44971952
The cDNAs encoding Xenopus laevis prolactin (PRL) and the alpha and beta subunits of thyroid-stimulating hormone (TSH alpha and…
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Highly Cited
1993
Highly Cited
1993
A thyrotrope-specific variant of Pit-1 transactivates the thyrotropin beta promoter.
B. Haugen
,
W. Wood
,
D. Gordon
,
E. Ridgway
Journal of Biological Chemistry
1993
Corpus ID: 21639109
Highly Cited
1991
Highly Cited
1991
Thyroid hormone decreases the stability and the poly(A) tract length of rat thyrotropin beta-subunit messenger RNA.
I. Krane
,
E. Spindel
,
William W. Chin
Molecular Endocrinology
1991
Corpus ID: 29548369
Thyroid hormone (T3 and T4) down-regulation of TSH subunit steady state mRNA levels and subunit gene transcription in vitro and…
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Highly Cited
1989
Highly Cited
1989
Expression of biologically active human follitropin in Chinese hamster ovary cells.
J. L. Keene
,
M. Matzuk
,
+4 authors
I. Boime
Journal of Biological Chemistry
1989
Corpus ID: 39282944
Highly Cited
1988
Highly Cited
1988
Cloning of the human thyrotropin beta-subunit gene and transient expression of biologically active human thyrotropin after gene transfection.
F. Wondisford
,
S. Usala
,
+7 authors
B. Carter
Molecular Endocrinology
1988
Corpus ID: 29550882
A 17 kilobase pair fragment of DNA containing the human TSH (hTSH) beta-subunit gene was isolated from a human leukocyte genomic…
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Highly Cited
1985
Highly Cited
1985
Transcriptional regulation of the thyrotropin subunit genes by thyroid hormone.
M. Shupnik
,
W. Chin
,
J. Habener
,
E. Ridgway
Journal of Biological Chemistry
1985
Corpus ID: 31663563
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