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Thyrotropin, beta Subunit

Known as: TSH beta, Thyrotropin beta, Thyrotropin, beta Chain 
The beta subunit of thyroid stimulating hormone, thyrotropin. It is a 112-amino acid glycopolypeptide of about 16 kD. Full biological activity of TSH… 
National Institutes of Health

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In BloodProcess of secretionTSHB geneagonists

Papers overview

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Highly Cited
1999
Highly Cited
1999
Ligand‐induced recruitment of a histone deacetylase in the negative‐feedback regulation of the thyrotropin β gene
We have investigated ligand‐dependent negative regulation of the thyroid‐stimulating hormone β (TSHβ) gene. Thyroid hormone (T3… 
Highly Cited
1999
Highly Cited
1999
Central hypothyroidism associated with retinoid X receptor-selective ligands.
BACKGROUND The occurrence of symptomatic central hypothyroidism (characterized by low serum thyrotropin and thyroxine… 
Highly Cited
1996
Highly Cited
1996
A soluble transcription factor, Oct-1, is also found in the insoluble nuclear matrix and possesses silencing activity in its alanine-rich domain
Expression of the human thyrotropin beta (hTSHbeta) gene is restricted to thyrotrophs, at least in part, by silencing. Using… 
Highly Cited
1994
Highly Cited
1994
Different effects of continuous infusion of interleukin-1 and interleukin-6 on the hypothalamic-hypophysial-thyroid axis.
The cytokines interleukin-1 (IL-1) and IL-6 are thought to be important mediators in the suppression of thyroid function during… 
Highly Cited
1993
Highly Cited
1993
A thyrotrope-specific variant of Pit-1 transactivates the thyrotropin beta promoter.
Highly Cited
1993
Highly Cited
1993
Expression of the Xenopus laevis prolactin and thyrotropin genes during metamorphosis.
The cDNAs encoding Xenopus laevis prolactin (PRL) and the alpha and beta subunits of thyroid-stimulating hormone (TSH alpha and… 
Highly Cited
1991
Highly Cited
1991
Thyroid hormone decreases the stability and the poly(A) tract length of rat thyrotropin beta-subunit messenger RNA.
Thyroid hormone (T3 and T4) down-regulation of TSH subunit steady state mRNA levels and subunit gene transcription in vitro and… 
Highly Cited
1989
Highly Cited
1989
Expression of biologically active human follitropin in Chinese hamster ovary cells.
Highly Cited
1988
Highly Cited
1988
Cloning of the human thyrotropin beta-subunit gene and transient expression of biologically active human thyrotropin after gene transfection.
A 17 kilobase pair fragment of DNA containing the human TSH (hTSH) beta-subunit gene was isolated from a human leukocyte genomic… 
Highly Cited
1985
Highly Cited
1985
Transcriptional regulation of the thyrotropin subunit genes by thyroid hormone.
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