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Thyroid Hormone Receptor Beta

Known as: Nuclear Receptor Subfamily 1 Group A Member 2, Thyroid Hormone Receptors beta [Chemical/Ingredient], Gene Products, ERBA2 
High affinity receptors for THYROID HORMONES, especially TRIIODOTHYRONINE. These receptors are usually found in the nucleus where they regulate DNA… 
National Institutes of Health

Related topics

Related topics

29 relations
Biologic DevelopmentCell Differentiation processCell NucleusCell Proliferation

Narrower (2)

Thyroid Hormone Receptor beta-1Thyroid Hormone Receptor beta-2

Papers overview

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Highly Cited
2010
Highly Cited
2010
Expression of uncoupling protein 1 in mouse brown adipose tissue is thyroid hormone receptor-beta isoform specific and required for adaptive thermogenesis.
Cold-induced adaptive (or nonshivering) thermogenesis in small mammals is produced primarily in brown adipose tissue (BAT). BAT… 
Review
2005
Review
2005
Thyroid hormone receptor mutations and disease: beyond thyroid hormone resistance
Highly Cited
2002
Highly Cited
2002
Requirement for thyroid hormone receptor beta in T3 regulation of cholesterol metabolism in mice.
T3 potently influences cholesterol metabolism through the nuclear thyroid hormone receptor beta (TRbeta), the most abundant TR… 
Highly Cited
2000
Highly Cited
2000
Cloning and Characterization of Two Novel Thyroid Hormone Receptor β Isoforms
ABSTRACT Thyroid hormone (T3) activates nuclear receptor transcription factors, encoded by the TRα (NR1A1) and TRβ (NR1A2) genes… 
Highly Cited
1996
Highly Cited
1996
Dominant inheritance of resistance to thyroid hormone not linked to defects in the thyroid hormone receptor alpha or beta genes may be due to a defective cofactor.
Resistance to thyroid hormone (RTH) is an inherited syndrome of reduced tissue responsiveness to thyroid hormone. To date, all… 
Highly Cited
1995
Highly Cited
1995
Do clinical manifestations of resistance to thyroid hormone correlate with the functional alteration of the corresponding mutant thyroid hormone-beta receptors?
Resistance to thyroid hormone (RTH), a syndrome characterized by variable tissue hyposensitivity to thyroid hormone, is linked to… 
Highly Cited
1994
Highly Cited
1994
Spectrum of transcriptional, dimerization, and dominant negative properties of twenty different mutant thyroid hormone beta-receptors in thyroid hormone resistance syndrome.
Resistance to thyroid hormone (RTH) is usually dominantly inherited and characterized by elevated thyroid hormone levels… 
Highly Cited
1994
Highly Cited
1994
Widespread distribution of immunoreactive thyroid hormone beta 2 receptor (TR beta 2) in the nuclei of extrapituitary rat tissues.
Messenger RNA for thyroid hormone receptor (TR) isoforms alpha 1 and beta 1 are widely distributed in rat tissues. Until recently… 
Highly Cited
1991
Highly Cited
1991
Analysis of gene amplification in head‐and‐neck squamous‐cell carcinomas
The presence of gene amplification was determined in 66 fresh head‐and‐neck SCC specimens using a battery of 9 different probes… 
Highly Cited
1989
Highly Cited
1989
Generalized resistance to thyroid hormone associated with a mutation in the ligand-binding domain of the human thyroid hormone receptor beta.
The syndrome of generalized resistance to thyroid hormone is characterized by elevated circulating levels of thyroid hormone in… 
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