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Thymic Tissue

Known as: THYMUS 
Tissue composed of a highly cellular outer cortex, and less cellular inner medulla. Both cortex and medulla contain epithelial cells, interdigitating… Expand
National Institutes of Health

Papers overview

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Review
2008
Review
2008
Regulatory T cells (Tregs) play an indispensable role in maintaining immunological unresponsiveness to self-antigens and in… Expand
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Highly Cited
2003
Highly Cited
2003
CD4+CD25+ regulatory T cells (Treg) are instrumental in the maintenance of immunological tolerance. One critical question is… Expand
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Highly Cited
1998
Highly Cited
1998
The thymus represents the major site of the production and generation of T cells expressing αβ-type T-cell antigen receptors. Age… Expand
Review
1997
Review
1997
I thank Drs. D. V. Goeddel and P. Golstein for helpful comments on the manuscript. I am grateful to all members of my laboratory… Expand
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Review
1997
Review
1997
Interferons are cytokines that play a complex and central role in the resistance of mammalian hosts to pathogens. Type I… Expand
Highly Cited
1993
Highly Cited
1993
THE p53 tumour suppressor gene is the most widely mutated gene in human tumorigenesis1,2. p53 encodes a transcriptional… Expand
Highly Cited
1992
Highly Cited
1992
Fas antigen is a cell-surface protein that mediates apoptosis. It is expressed in various tissues including the thymus and has… Expand
Highly Cited
1991
Highly Cited
1991
Corticosteroids, calcium ionophores and anti-CD3 monoclonal antibodies kill mouse thymocytes incubated in vitro. Cell death is… Expand
Highly Cited
1978
Highly Cited
1978
Several soluble factors have recently been associated with the proliferation and differentiation of thymus-derived lymphocytes… Expand
Highly Cited
1973
Highly Cited
1973
A rapid method is described for effectively removing immunoglobulin‐bearing cells from either primed or unprimed mouse spleen and… Expand