Thrombopoietin Measurement

Known as: THRMPTN, Thrombopoietin 
The determination of the amount of thrombopoietin hormone present in a sample.
National Institutes of Health

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CDISC SDTM Laboratory Test Terminology by CodeCDISC SDTM Laboratory Test Terminology by NameClinical Data Interchange Standards Consortium TerminologyThrombopoietin
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Papers overview

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Review
2009
Review
2009
Thrombopoietin and thrombopoietin mimetics in the treatment of thrombocytopenia.
Although the thrombopoietin receptor was discovered in 1991 and thrombopoietin (TPO) was purified in 1994, the development of a… (More)
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Highly Cited
1998
Highly Cited
1998
Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin.
Thrombopoietin (TPO) acts as a lineage-specific late-acting factor to stimulate megakaryocyte and platelet formation. However… (More)
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Highly Cited
1997
Highly Cited
1997
Thrombopoietin levels in patients with cirrhosis before and after orthotopic liver transplantation.
Thrombocytopenia in patients with cirrhosis has historically been attributed to hypersplenism. Radiolabeled platelet studies have… (More)
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1997
1997
Human platelets display high-affinity receptors for thrombopoietin.
Thrombopoietin (Tpo) is a major regulator of megakaryopoiesis both in vivo and in vitro. Tpo initiates its biologic effects by… (More)
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Highly Cited
1997
Highly Cited
1997
Thrombopoietin signal transduction in purified murine megakaryocytes.
Thrombopoietin (TPO) is a recently cloned cytokine that binds to its receptor, Mpl, and promotes hematopoietic expansion and… (More)
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Highly Cited
1996
Highly Cited
1996
Circulating thrombopoietin level in chronic immune thrombocytopenic purpura.
The circulating thrombopoietin (TPO) level in 43 patients with chronic immune thrombocytopenic purpura (ITP) was examined by an… (More)
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Highly Cited
1996
Highly Cited
1996
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
Thrombopoietin (TPO) has recently been cloned and shown to regulate megakaryocyte and platelet production by activating the… (More)
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Highly Cited
1996
Highly Cited
1996
Low levels of erythroid and myeloid progenitors in thrombopoietin-and c-mpl-deficient mice.
Thrombopoietin (TPO), the ligand for the c-mpl receptor, has been shown to be the major regulator of platelet production. Mice… (More)
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Highly Cited
1996
Highly Cited
1996
A sensitive sandwich ELISA for measuring thrombopoietin in human serum: serum thrombopoietin levels in healthy volunteers and in patients with haemopoietic disorders.
A sensitive sandwich enzyme-linked immunosorbent assay (ELISA) has been established to estimate serum thrombopoietin (TPO… (More)
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Highly Cited
1995
Highly Cited
1995
Thrombopoietin (c-mpl ligand) acts synergistically with erythropoietin, stem cell factor, and interleukin-11 to enhance murine megakaryocyte colony growth and increases megakaryocyte ploidy in vitro.
Thrombopoietin (Tpo), the ligand for the c-mpl receptor, is a major regulator of platelet production in vivo. Treatment of mice… (More)
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