Thioflavin S
National Institutes of Health
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The development of neurotherapeutics for many neurodegenerative diseases has largely been hindered by limited pharmacologic…
We previously demonstrated the normal mouse epididymal lumen contains a non‐pathological amyloid matrix that surrounds…
The aggregation processes of amyloid-β-(16-22) peptides (Aβ16-22) are investigated by atomic force microscopy (AFM). It is found…
Parkinson's disease (PD) and diabetes belong to the most common neurodegenerative and metabolic syndromes, respectively…
Binding of histological benzothiazole dye thioflavin S (ThS) to protein aggregates has been related with the presence of amyloid…
Lipophilic analogs of thioflavin S were synthesized and radiolabeled with positron or single photon emitting radionuclides. The…
Despite extensive deposition of putatively neurotoxic amyloid-β (Aβ) protein in the brain, it has not been possible to…
Amyloid beta peptides (A beta) are deposited in the brains of Alzheimer's disease (AD) and elderly Down's syndrome (DS) patients…