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Thienopyridines

Known as: Thienopyridine Derivatives, Platelet ADP Receptor Antagonist, Derivatives, Thienopyridine 
A class of agents that target at platelet ADP receptor or purinergic receptor P2RY12 with antiplatelet activity.
National Institutes of Health

Papers overview

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Highly Cited
2011
Highly Cited
2011
BACKGROUND Preoperative treatment with thienopyridines is associated with increased postoperative bleeding in cardiac surgery… Expand
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Review
2011
Review
2011
Summary.  The most important adverse effect of antithrombotic treatment is the occurrence of bleeding. In the case of severe… Expand
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Review
2010
Review
2010
ACCF/ACG/AHA 2010 Expert Consensus Document on the Concomitant Use of Proton Pump Inhibitors and Thienopyridines: A Focused… Expand
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Review
2010
Review
2010
A denosine diphosphate (ADP) plays a key role in the genesis of physiological platelet-rich hemostatic plugs and of pathological… Expand
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Highly Cited
2007
Highly Cited
2007
Summary.  Background: Thienopyridines are metabolized to active metabolites that irreversibly inhibit the platelet P2Y12… Expand
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Highly Cited
2007
Highly Cited
2007
BACKGROUND The aim of this study was to compare rate of onset, magnitude, and consistency of platelet inhibition after… Expand
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Highly Cited
2006
Highly Cited
2006
The biotransformation of prasugrel to R-138727 (2-[1-2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4-mercapto-3-piperidinylidene… Expand
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Highly Cited
2006
Highly Cited
2006
Background: The risks and benefits of coxibs, non-steroidal anti-inflammatory drugs (NSAIDs), and aspirin treatment are under… Expand
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Review
2004
Review
2004
This chapter about antithrombotic therapy for coronary artery disease (CAD) is part of the Seventh ACCP Conference on… Expand
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Highly Cited
2000
Highly Cited
2000
CS‐747 is a novel antiplatelet agent that generates an active metabolite, R‐99224, in vivo. CS‐747 itself was totally inactive in… Expand
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