Therapeutic Targets Database

Known as: TTD, Therapeutic target 
Therapeutic Target Database (TTD) is a database provided by Bioinformatics and Drug Design Group in National University of Singapore, which provides… (More)
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Papers overview

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2017
2017
Open Targets: a platform for therapeutic target identification and validation
We have designed and developed a data integration and visualization platform that provides evidence about the association of… (More)
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2016
2016
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
Extensive drug discovery efforts have yielded many approved and candidate drugs targeting various targets in different biological… (More)
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Highly Cited
2011
Highly Cited
2011
HIT: linking herbal active ingredients to targets
The information of protein targets and small molecule has been highly valued by biomedical and pharmaceutical research. Several… (More)
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Highly Cited
2010
Highly Cited
2010
Update of TTD: Therapeutic Target Database
Increasing numbers of proteins, nucleic acids and other molecular entities have been explored as therapeutic targets, hundreds of… (More)
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Review
2008
Review
2008
Remyelination in the CNS: from biology to therapy
Remyelination involves reinvesting demyelinated axons with new myelin sheaths. In stark contrast to the situation that follows… (More)
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Highly Cited
2007
Highly Cited
2007
PDTD: a web-accessible protein database for drug target identification
Target identification is important for modern drug discovery. With the advances in the development of molecular docking… (More)
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Highly Cited
2005
Highly Cited
2005
Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury.
The mechanism of apoptosis has been extensively characterized over the past decade, but little is known about alternative forms… (More)
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Review
2004
Review
2004
Regulation of endothelial nitric oxide synthase by tetrahydrobiopterin in vascular disease.
Nitric oxide (NO), produced by endothelial nitric oxide synthase (eNOS), is a key signaling molecule in vascular homeostasis… (More)
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Highly Cited
2002
Highly Cited
2002
TTD: Therapeutic Target Database
A number of proteins and nucleic acids have been explored as therapeutic targets. These targets are subjects of interest in… (More)
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Highly Cited
2000
Highly Cited
2000
The cyclooxygenase-2 inhibitor celecoxib is a potent preventive and therapeutic agent in the min mouse model of adenomatous polyposis.
Epidemiological and animal studies suggest that nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce colon cancer risk… (More)
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