Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 227,741,290 papers from all fields of science
Search
Sign In
Create Free Account
Therapeutic Equivalency Study
Known as:
BIO-EQUIVALENCE
A study most often used to compare the efficacy of different formulations to treat a given disease. It is the testing of an old versus a new…
Expand
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
2 relations
CDISC SDTM Trial Type Terminology
Clinical Data Interchange Standards Consortium Terminology
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2015
Review
2015
Biowaiver Monographs for Immediate-Release Solid Oral Dosage Forms: Nifedipine.
Jayachandar Gajendran
,
J. Krämer
,
+7 authors
J. Dressman
Journal of Pharmacy and Science
2015
Corpus ID: 22879736
Literature data relevant to the biopharmaceutical properties of the active pharmaceutical ingredient (API) nifedipine are…
Expand
2013
2013
Quantitative assessment of the switchability of generic products.
V. Karalis
,
M. Bialer
,
P. Macheras
European Journal of Pharmaceutical Sciences
2013
Corpus ID: 1380676
2012
2012
Use of Partial AUC (PAUC) to Evaluate Bioequivalence—A Case Study with Complex Absorption: Methylphenidate
Jeanne Fourie Zirkelbach
,
A. Jackson
,
Yaning Wang
,
Donald J. Schuirmann
Pharmaceutical Research
2012
Corpus ID: 7156199
Methylphenidate modified-release products produce early and late peak concentrations critical for treatment of morning and…
Expand
2011
2011
Study on dissolution and absorption of four dosage forms of isosorbide mononitrate: level A in vitro-in vivo correlation.
Zi-qiang Li
,
Xin He
,
+5 authors
Shu-jun Sun
European journal of pharmaceutics and…
2011
Corpus ID: 13604660
2010
2010
Examining the role of metabolites in bioequivalence assessment.
V. Karalis
,
P. Macheras
Journal of Pharmacy & Pharmaceutical Sciences
2010
Corpus ID: 14503613
PURPOSE Investigate the role of metabolites in bioequivalence (BE) assessment. METHODS. Sets of ordinary differential equations…
Expand
Highly Cited
2003
Highly Cited
2003
Limits for the Scaled Average Bioequivalence of Highly Variable Drugs and Drug Products
L. Tothfalusi
,
L. Endrenyi
Pharmaceutical Research
2003
Corpus ID: 22943213
AbstractPurpose. To provide a rational procedure for establishing regulatory bioequivalence (BE) limits that can be applied in…
Expand
2003
2003
Scaling or wider bioequivalence limits for highly variable drugs and for the special case of C(max).
L. Tothfalusi
,
L. Endrenyi
,
K. Midha
International journal of clinical pharmacology…
2003
Corpus ID: 6839438
OBJECTIVE To illustrate that bioequivalence (BE) can be effectively evaluated for highly variable (HV) drugs and drug products…
Expand
2003
2003
Pharmacodynamic considerations in bioequivalence assessment: comparison of novel and existing metrics.
V. Karalis
,
P. Macheras
European Journal of Pharmaceutical Sciences
2003
Corpus ID: 25528618
2002
2002
A practical approach for comparing means of two groups without equal variance assumption
Hansheng Wang
,
S. Chow
Statistics in Medicine
2002
Corpus ID: 2454426
In this paper we consider two‐groups of i.i.d. normally distributed random variables (N(μx,σx2) and N(μy,σy2)) without assuming…
Expand
1994
1994
Comparison of Single and Multiple Dose Pharmacokinetics Using Clinical Bioequivalence Data and Monte Carlo Simulations
A. El-Tahtawy
,
A. Jackson
,
T. Ludden
Pharmaceutical Research
1994
Corpus ID: 22289352
The purpose of this study was to evaluate the relative performance and usefulness of single dose (SD) and multiple dose (MD…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE