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Thebaine

Known as: Morphinan, 6,7,8,14-tetradehydro-4,5-epoxy-3,6-dimethoxy-17-methyl-, (5alpha)-, Thebaine [Chemical/Ingredient], 4,5alpha-Epoxy-3,6-dimethoxy-17-methyl-6,8-morphinadien 
A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than… 
National Institutes of Health

Related topics

Related topics

16 relations

Narrower (6)

ASM 5-10NIH 10236bractazoninedrotebanol

Broader (2)

ConvulsantsNarcotics
In BloodThebaine:MCnc:Pt:Ser/Plas:Qnagonistsanalogs & derivatives

Papers overview

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Highly Cited
2015
Highly Cited
2015
Complete biosynthesis of opioids in yeast
Toward opioids without poppy fields Producing opioids without having to depend on field-grown poppies would be of great benefit… 
Review
2013
Review
2013
Mu Opioids and Their Receptors: Evolution of a Concept
Opiates are among the oldest medications available to manage a number of medical problems. Although pain is the current focus… 
Highly Cited
2011
Highly Cited
2011
Extraction and determination of opium alkaloids in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography.
Highly Cited
2004
Highly Cited
2004
RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy
We report on the silencing of codeinone reductase (COR) in the opium poppy, Papaver somniferum, using a chimeric hairpin RNA… 
Highly Cited
2000
Highly Cited
2000
Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somninferum.
Highly Cited
1998
Highly Cited
1998
Opiate concentrations following the ingestion of poppy seed products--evidence for 'the poppy seed defence'.
Highly Cited
1994
Highly Cited
1994
Antagonists at excitatory opioid receptors on sensory neurons in culture increase potency and specificity of opiate analgesics and attenuate development of tolerance/dependence
Highly Cited
1986
Highly Cited
1986
Opioid Analgesics: Chemistry and Receptors
1. Introduction.- 2. 4,5-Epoxymorphinans.- 3. Morphinans.- 4. Benzomorphans.- 5. Arylmorphans and Related Compounds.- 6… 
Highly Cited
1979
Highly Cited
1979
Morphine derivatives with diminished opiate receptor potency show enhanced central excitatory activity
Highly Cited
1968
Highly Cited
1968
The addiction cycle to narcotics in the rat and its relation to catecholamines.
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