Thebaine

Known as: Morphinan, 6,7,8,14-tetradehydro-4,5-epoxy-3,6-dimethoxy-17-methyl-, (5alpha)-, Thebaine [Chemical/Ingredient], 4,5alpha-Epoxy-3,6-dimethoxy-17-methyl-6,8-morphinadien 
A drug that is derived from opium, which contains from 0.3-1.5% thebaine depending on its origin. It produces strychnine-like convulsions rather than… (More)
National Institutes of Health

Related topics

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14 relations

Narrower (5)

ASM 5-10NIH 10236drotebanolhybromet
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Broader (2)

ConvulsantsNarcotics
In Bloodagonistsanalogs & derivativesantagonists & inhibitors
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Papers overview

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Highly Cited
2015
Highly Cited
2015
Complete biosynthesis of opioids in yeast
Opioids are the primary drugs used in Western medicine for pain management and palliative care. Farming of opium poppies remains… (More)
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Highly Cited
2014
Highly Cited
2014
A microbial biomanufacturing platform for natural and semi-synthetic opiates
Opiates and related molecules are medically essential, but their production via field cultivation of opium poppy Papaver… (More)
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Review
2013
Review
2013
Mu opioids and their receptors: evolution of a concept.
Opiates are among the oldest medications available to manage a number of medical problems. Although pain is the current focus… (More)
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2012
2012
Real Time Implementation of Digital Watermarking Algorithm for Image and Video Application
Watermarking is the process of hiding a predefined pattern or logo into multimedia like image, audio or video in a way that… (More)
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Highly Cited
2010
Highly Cited
2010
Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.
Two previously undetected enzymes involved in morphine biosynthesis and unique among plants to opium poppy have been identified… (More)
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Highly Cited
2004
Highly Cited
2004
RNAi-mediated replacement of morphine with the nonnarcotic alkaloid reticuline in opium poppy
We report on the silencing of codeinone reductase (COR) in the opium poppy, Papaver somniferum, using a chimeric hairpin RNA… (More)
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1995
1995
Production of monoclonal antibodies and ELISA for thebaine and codeine
The ratio of hapten and bovine serum albumin in antigen conjugate was exactly determined by matrix-assisted laser desorption… (More)
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1995
1995
Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis.
Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase, a highly substrate-specific enzyme, has been purified nearly 3,000-fold to… (More)
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1988
1988
Transformation of thebaine to oripavine, codeine, and morphine by rat liver, kidney, and brain microsomes.
Thebaine, an intermediate of morphine biosynthesis in the poppy plant, Papaver somniferum, was transformed to oripavine, codeine… (More)
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1975
1975
Antagonism of the convulsant effects of heroin, d-propoxyphene, meperidine, normeperidine and thebaine by naloxone in mice.
Naloxone antagonized convulsions produced by tail vein infusions of d-propoxyphene, heroin, meperidine, normeperidine and… (More)
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