Testicular malignant germ cell tumor

Known as: Malignant Germ Cell Neoplasm of the Testis, Testicular Germ Cell Cancer, Testicular ca. (no germ/tropho.) 
Cancer that forms in tissues of the testis (one of two egg-shaped glands inside the scrotum that make sperm and male hormones). Testicular cancer… (More)
National Institutes of Health

Related topics

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AneuploidyBEP regimenCryptorchidismEtoposide-Platinol Regimen
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carcinoma of the testis

Papers overview

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Highly Cited
2010
Highly Cited
2010
Variants near DMRT1, TERT and ATF7IP are associated with testicular germ cell cancer
We conducted a genome-wide association study for testicular germ cell tumor, genotyping 298,782 SNPs in 979 affected individuals… (More)
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Highly Cited
2009
Highly Cited
2009
Common variation in KITLG and at 5q31.3 predisposes to testicular germ cell cancer
Testicular germ cell tumors (TGCT) have been expected to have a strong underlying genetic component. We conducted a genome-wide… (More)
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Highly Cited
2008
Highly Cited
2008
Identification in rats of a programming window for reproductive tract masculinization, disruption of which leads to hypospadias and cryptorchidism.
Becoming a phenotypic male is ultimately determined by androgen-induced masculinization. Disorders of fetal masculinization… (More)
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Review
2003
Review
2003
The timing of normal puberty and the age limits of sexual precocity: variations around the world, secular trends, and changes after migration.
During the past decade, possible advancement in timing of puberty has been reported in the United States. In addition, early… (More)
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Highly Cited
2002
Highly Cited
2002
Curing metastatic testicular cancer.
Our initial studies with cisplatin + vinblastine + bleomycin began 27 years ago in 1974, changing the cure rate for disseminated… (More)
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Review
2001
Review
2001
Testicular dysgenesis syndrome: an increasingly common developmental disorder with environmental aspects.
Numerous reports have recently focused on various aspects of adverse trends in male reproductive health, such as the rising… (More)
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Highly Cited
2001
Highly Cited
2001
Organ sparing surgery for malignant germ cell tumor of the testis.
PURPOSE We evaluate the indication, technique and long-term outcome of organ preserving tumor resection rather than standard… (More)
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Highly Cited
2001
Highly Cited
2001
Altered expression of Ape1/ref-1 in germ cell tumors and overexpression in NT2 cells confers resistance to bleomycin and radiation.
The human AP endonuclease (Ape1 or ref-1) DNA base excision repair (BER) enzyme is a multifunctional protein that has an impact… (More)
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Highly Cited
2000
Highly Cited
2000
Cardiovascular morbidity in long-term survivors of metastatic testicular cancer.
PURPOSE To determine whether long-term survivors of metastatic testicular cancer have an increased risk of cardiovascular… (More)
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Highly Cited
1996
Highly Cited
1996
Evaluation of long-term toxicity after chemotherapy for testicular cancer.
PURPOSE The current study evaluates the extent and reversibility of late sequelae after chemotherapy in longterm survivors of… (More)
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