Tauroursodeoxycholate

 
National Institutes of Health

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2011
2011
AIMS Hyperplasia of vascular smooth muscle cells (VSMCs) after blood vessel injury is one of the major pathophysiological… (More)
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Highly Cited
2002
Highly Cited
2002
BACKGROUND & AIMS Hepatic bile salt secretion is an essential function of vertebrate liver. Rat and mouse bile salt export pump… (More)
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2002
2002
BACKGROUND Tauroursodeoxycholate (TUDC) provides partial protection against taurolithocholate (TLC) induced cholestasis, possibly… (More)
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Highly Cited
1999
Highly Cited
1999
The rat liver organic anion transporting polypeptide (Oatp1) has been extensively characterized mainly in the Xenopus laevis… (More)
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Highly Cited
1998
Highly Cited
1998
Canalicular secretion of bile salts is a vital function of the vertebrate liver, yet the molecular identity of the involved ATP… (More)
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1998
1998
BACKGROUND/AIMS Ethanol impairs cellular antioxidant defense and protein metabolism. Hydrophilic bile acids are protective… (More)
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1993
1993
Cytoprotection by tauroursodeoxycholic acid and tauro-beta-muricholic acid against taurochenodeoxycholic acid-induced toxicity… (More)
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1990
1990
Ursodeoxycholate has been advocated for the treatment of cholestatic liver diseases. The coinfusion of tauroursodeoxycholate with… (More)
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Highly Cited
1990
Highly Cited
1990
Continuous intravenous infusion of taurochenodeoxycholate at a rate of 0.4 mumol.min-1.100 gm-1 for only 30 min in rats caused… (More)
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Highly Cited
1989
Highly Cited
1989
This paper describes the derivation of a bile salt monomeric hydrophobicity index that quantitatively defines the composite… (More)
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