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Target Lesion Identification

Known as: TARGET 
The identification of a lesion that is present at baseline, is measurable and is the primary target of the therapeutic intervention.
National Institutes of Health

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Related topics

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Clinical Data Interchange Standards Consortium Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Long non-coding RNA MALAT1 is upregulated and involved in cell proliferation, migration and apoptosis in ovarian cancer.
Ovarian cancer (OC) is the leading cause of mortality among gynecological malignancies. Although microRNAs are known to have a… Expand
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Highly Cited
2016
Highly Cited
2016
Reducing emissions from agriculture to meet the 2 °C target.
More than 100 countries pledged to reduce agricultural greenhouse gas (GHG) emissions in the 2015 Paris Agreement of the United… Expand
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Review
2016
Review
2016
miRNA-124 in Immune System and Immune Disorders
In recent years, miR-124 has emerged as a critical modulator of immunity and inflammation. Here, we summarize studies on the… Expand
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Review
2016
Review
2016
Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target
The cyclic AMP response element binding (CREB) protein has pleiotropic activities in physiologic processes. Due to its central… Expand
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Review
2015
Review
2015
Targeting Cdc20 as a novel cancer therapeutic strategy.
The Anaphase Promoting Complex (APC, also called APC/C) regulates cell cycle progression by forming two closely related, but… Expand
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2014
2014
2014 Eighth Joint National Committee panel recommendation for blood pressure targets revisited: results from the INVEST study.
BACKGROUND The 2014 Eighth Joint National Committee panel recommendations for management of high blood pressure (BP) recommend a… Expand
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2010
2010
t-SNARE Protein Conformations Patterned by the Lipid Microenvironment*
The spatial distribution of the target (t-)SNARE proteins (syntaxin and SNAP-25) on the plasma membrane has been extensively… Expand
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2008
2008
Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line.
Natural killer cells recognize and induce apoptosis in foreign, transformed or virus-infected cells through the release of… Expand
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1990
1990
The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters.
We describe an unusual element that activates the synthesis of short transcripts from a wide variety of mRNA and small nuclear… Expand
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1986
1986
Further observations on the occurrence of express-saccades in the monkey
SummaryExpress-saccades, i.e. goal directed eye movements with extremely short saccadic reaction times (SRT) have recently been… Expand
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