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Target Lesion Identification

Known as: TARGET 
The identification of a lesion that is present at baseline, is measurable and is the primary target of the therapeutic intervention.
National Institutes of Health

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Clinical Data Interchange Standards Consortium Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Long non-coding RNA MALAT1 is upregulated and involved in cell proliferation, migration and apoptosis in ovarian cancer.
Ovarian cancer (OC) is the leading cause of mortality among gynecological malignancies. Although microRNAs are known to have a… 
Highly Cited
2017
Highly Cited
2017
Pharmaceutical versatility of cationic niosomes derived from amino acid-based surfactants: Skin penetration behavior and controlled drug release.
Review
2016
Review
2016
Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target
The cyclic AMP response element binding (CREB) protein has pleiotropic activities in physiologic processes. Due to its central… 
Review
2015
Review
2015
Therapeutic strategies targeting cancer stem cells
Cancer stem cells (CSCs) are undifferentiated cancer cells with a high tumorigenic activity, the ability to undergo self‐renewal… 
2014
2014
Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy
Macrophage inhibitory factor 1 (MIC1) is frequently altered in various cancers. The aim of this study was to investigate the… 
Highly Cited
2013
Highly Cited
2013
Direct label free ultrasensitive impedimetric DNA biosensor using dendrimer functionalized GaN nanowires.
2008
2008
Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line.
2004
2004
Further observations on the occurrence of express-saccades in the monkey
SummaryExpress-saccades, i.e. goal directed eye movements with extremely short saccadic reaction times (SRT) have recently been… 
2001
2001
Role of SNAP-23 in trafficking of H+-ATPase in cultured inner medullary collecting duct cells.
The trafficking of H+-ATPase vesicles to the apical membrane of inner medullary collecting duct (IMCD) cells utilizes a mechanism… 
Highly Cited
1990
Highly Cited
1990
The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters.
We describe an unusual element that activates the synthesis of short transcripts from a wide variety of mRNA and small nuclear… 
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