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Target Lesion Identification

Known as: TARGET 
The identification of a lesion that is present at baseline, is measurable and is the primary target of the therapeutic intervention.
National Institutes of Health

Related topics

Related topics

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Clinical Data Interchange Standards Consortium Terminology

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Angiogenesis biomarkers and their targeting ligands as potential targets for tumor angiogenesis
Angiogenesis is known as one of the hallmarks in cancer which could play a key role in providing oxygen and nutrients for tumor… Expand
2017
2017
Long non-coding RNA MALAT1 is upregulated and involved in cell proliferation, migration and apoptosis in ovarian cancer.
Ovarian cancer (OC) is the leading cause of mortality among gynecological malignancies. Although microRNAs are known to have a… Expand
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Highly Cited
2016
Highly Cited
2016
Reducing emissions from agriculture to meet the 2 °C target.
More than 100 countries pledged to reduce agricultural greenhouse gas (GHG) emissions in the 2015 Paris Agreement of the United… Expand
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Review
2016
Review
2016
Control of CREB expression in tumors: from molecular mechanisms and signal transduction pathways to therapeutic target
The cyclic AMP response element binding (CREB) protein has pleiotropic activities in physiologic processes. Due to its central… Expand
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Highly Cited
2014
Highly Cited
2014
2014 Eighth Joint National Committee panel recommendation for blood pressure targets revisited: results from the INVEST study.
BACKGROUND The 2014 Eighth Joint National Committee panel recommendations for management of high blood pressure (BP) recommend a… Expand
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2014
2014
Macrophage inhibitory factor 1 acts as a potential biomarker in patients with esophageal squamous cell carcinoma and is a target for antibody-based therapy
Macrophage inhibitory factor 1 (MIC1) is frequently altered in various cancers. The aim of this study was to investigate the… Expand
Highly Cited
2010
Highly Cited
2010
t-SNARE Protein Conformations Patterned by the Lipid Microenvironment*
The spatial distribution of the target (t-)SNARE proteins (syntaxin and SNAP-25) on the plasma membrane has been extensively… Expand
Highly Cited
2004
Highly Cited
2004
Further observations on the occurrence of express-saccades in the monkey
SummaryExpress-saccades, i.e. goal directed eye movements with extremely short saccadic reaction times (SRT) have recently been… Expand
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2001
2001
Role of SNAP-23 in trafficking of H+-ATPase in cultured inner medullary collecting duct cells.
The trafficking of H+-ATPase vesicles to the apical membrane of inner medullary collecting duct (IMCD) cells utilizes a mechanism… Expand
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Highly Cited
1990
Highly Cited
1990
The HIV-1 long terminal repeat contains an unusual element that induces the synthesis of short RNAs from various mRNA and snRNA promoters.
We describe an unusual element that activates the synthesis of short transcripts from a wide variety of mRNA and small nuclear… Expand
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