TXY436

National Institutes of Health

Papers overview

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2014

2014

Inhibition of RND-type efflux pumps confers the FtsZ-directed prodrug TXY436 with activity against Gram-negative bacteria.

M. Kaul, Yongzhen Zhang, Ajit K. Parhi, E. LaVoie, D. S. Pilch
Biochemical pharmacology
2014
Corpus ID: 41919117

2013

2013

An FtsZ-Targeting Prodrug with Oral Antistaphylococcal Efficacy In Vivo

M. Kaul, L. Mark, Yongzhen Zhang, Ajit K. Parhi, E. LaVoie, D. S. Pilch
Antimicrobial Agents and Chemotherapy
2013
Corpus ID: 10192739

ABSTRACT The bacterial cell division protein FtsZ represents a novel antibiotic target that has yet to be exploited clinically…