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TXNIP gene

Known as: Thioredoxin Interacting Protein Gene, VITAMIN D3-UPREGULATED PROTEIN 1, THIOREDOXIN-INTERACTING PROTEIN 
This gene plays a role in the regulation of stress response signaling.
National Institutes of Health

Related topics

Related topics

6 relations
Environment-to-Cell CommunicationImmunityLigand BindingThioredoxin-Interacting Protein

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2017
2017
Deletion of TXNIP Mitigates High-Fat Diet-Impaired Angiogenesis and Prevents Inflammation in a Mouse Model of Critical Limb Ischemia
Background: Previous work demonstrated that high-fat diet (HFD) triggered thioredoxin-interacting protein (TXNIP) and that… 
2012
2012
In vivo redox state of human thioredoxin and redox shift by the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA).
2011
2011
Diminished AMPK signaling response to fasting in thioredoxin‐interacting protein knockout mice
Highly Cited
2010
Highly Cited
2010
Transcriptional and Translational Downregulation of Thioredoxin Interacting Protein Is Required for Metabolic Reprogramming during G(1).
Growth factor signaling drives increased glucose uptake and glycolysis-the Warburg effect-that supports macromolecular synthesis… 
2010
2010
Vitamin D3 Up-regulated Protein 1(VDUP1) Is Regulated by FOXO3A and miR-17-5p at the Transcriptional and Post-transcriptional Levels, Respectively, in Senescent Fibroblasts*
Vitamin D3 up-regulated protein 1 (VDUP1) plays multifunctional roles in diverse cellular responses, particularly in its relation… 
Highly Cited
2009
Highly Cited
2009
Insulin counteracts glucotoxic effects by suppressing thioredoxin-interacting protein production in INS-1E beta cells and in Psammomys obesus pancreatic islets
Aims/hypothesisIn type 2 diabetes, glucose toxicity leads to beta cell apoptosis with decreased beta cell mass as a consequence… 
2007
2007
A possible role of thioredoxin interacting protein in the pathogenesis of streptozotocin-induced diabetic nephropathy.
Oxidative stress has been suggested to play an important role in the pathogenesis of diabetic nephropathy because it increases… 
2005
2005
The shear stress of keeping arteries clear
The force exerted by blood as it flows through the vessels influences the development of atherosclerosis. An understanding of how… 
Highly Cited
2004
Highly Cited
2004
Oxidative stress and thioredoxin-interacting protein promote intravasation of melanoma cells.
Highly Cited
2001
Highly Cited
2001
Cloning, genetic characterization, and chromosomal mapping of the mouse VDUP1 gene.
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