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TWIST2 gene

Known as: TWIST, DROSOPHILA, HOMOLOG OF, 2, bHLHa39, Dermo-1 
This gene plays a role in the negative regulation of both gene transcription and osteoblast differentiation.
National Institutes of Health

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Homo sapiensNegative Regulation of Cell DifferentiationTWIST2 protein, humanTranscriptional Regulation

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TWIST2 wt Allele

Papers overview

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2018
2018
Remapping of the belted phenotype in cattle on BTA3 identifies a multiplication event as the candidate causal mutation
It has been known for almost a century that the belted phenotype in cattle follows a pattern of dominant inheritance. In 2009… 
2017
2017
Smoking and gender modify the effect of TWIST on patient survival in head and neck squamous carcinoma
Purpose TWIST is a critical factor for predicting prognosis in several human cancers. Here, we study the prognostic significance… 
2016
2016
MiR-186 acts as a tumor suppressor by targeting TWIST 1 / 2 and regulating the epithelial-mesenchymal transition in glioblastoma multiforme
Glioblastoma remains one of the most lethal types of cancer, and is the most common brain tumor in adults. The purpose of this… 
2016
2016
Abstract 2680: Development and application of a novel model of human lung-to-brain metastasis: identification of TWIST2 and SPOCK1 as unique regulators of brain metastases
Brain Metastases (BM) are the most common type of cerebral tumor in adult, occurring at a rate ten times greater than that of… 
2014
2014
Unwiring the transcriptional heat circuit
Mature adipocytes are postmitotic (1), and therefore development of adipocytes requires the proliferation and differentiation of… 
2013
2013
Conditional Deletion of Cytochrome P450 Reductase in Osteoprogenitor Cells Affects Long Bone and Skull Development in Mice Recapitulating Antley-Bixler Syndrome: Role of a Redox Enzyme in Development
NADPH-cytochrome P450 oxidoreductase (POR) is the primary electron donor for cytochromes P450, dehydrocholesterol reductase, heme… 
2010
2010
Differential methylation of CpG islands within the dermo1 gene promoter in several cancer cell lines.
Inactivation of tumor-related genes by promoter hypermethylation is a common epigenetic event in the development of variety of… 
2010
2010
Hypoxia inhibits osteogenesis through direct regulation of RUNX 2 by TWIST
INTRODUCTION: Bone loss induced by hypoxia is associated with various pathophysiological conditions such as ischemia, vascular… 
2009
2009
Twist2 regulates CD7 expression and galectin-1-induced apoptosis in mature T-cells
In the periphery, a galectin-1 receptor, CD7, plays crucial roles in galectin-1-mediated apoptosis of activated T-cells as well… 
2002
2002
Isolation of Dermo-1 as an SRG3-interacting protein by yeast two hybrid screening
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