FAQ

TWIST2 gene

Known as: TWIST, DROSOPHILA, HOMOLOG OF, 2, bHLHa39, Dermo-1 
This gene plays a role in the negative regulation of both gene transcription and osteoblast differentiation.
National Institutes of Health

Topic mentions per year

Topic mentions per year

1997-2018
0519972018

Related topics

Related topics

8 relations
Homo sapiensNegative Regulation of Cell DifferentiationTWIST2 protein, humanTranscriptional Regulation
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Narrower (1)

TWIST2 wt Allele

Related mentions per year

Related mentions per year

1937-2018
19401960198020002020
TWIST2 gene
Transcriptional Regulation
dna binding
Homo sapiens
Transcriptional Repression
Negative Regulation of Cell Differentiation

Papers overview

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2015
2015
TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer
Tumor budding in colorectal cancer is likened to an epithelial-mesenchymal transition (EMT) characterized predominantly by loss… (More)
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2015
2015
Recurrent Mutations in the Basic Domain of TWIST2 Cause Ablepharon Macrostomia and Barber-Say Syndromes.
Ablepharon macrostomia syndrome (AMS) and Barber-Say syndrome (BSS) are rare congenital ectodermal dysplasias characterized by… (More)
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2013
2013
Down-regulation of miR-138 promotes colorectal cancer metastasis via directly targeting TWIST2
Colorectal cancer (CRC) is the most common digestive system malignancy. The molecular events involved in the development and… (More)
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2012
2012
Correlation of TWIST2 up-regulation and epithelial-mesenchymal transition during tumorigenesis and progression of cervical carcinoma.
OBJECTIVE Globally, cervical cancer is the second most common cancer among women, and determining potential targets involved in… (More)
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2011
2011
Overexpression of TWIST2 correlates with poor prognosis in Head and Neck Squamous Cell Carcinomas
Head and neck squamous cell carcinomas (HNSCC) are a heterogeneous group of tumors with variable presentation and clinical… (More)
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2011
2011
Hypoxia-inducible factor-1 alpha, in association with TWIST2 and SNIP1, is a critical prognostic factor in patients with tongue squamous cell carcinoma.
It has become apparent that hypoxia and hypoxia-inducible factor-1 (HIF-1) activation have the potential of modulating the… (More)
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2010
2010
Homozygous nonsense mutations in TWIST2 cause Setleis syndrome.
The focal facial dermal dysplasias (FFDDs) are a group of inherited developmental disorders in which the characteristic… (More)
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2005
2005
TWIST2 demonstrates differential methylation in immunoglobulin variable heavy chain mutated and unmutated chronic lymphocytic leukemia.
PURPOSE Chronic lymphocytic leukemia (CLL) is a clinically heterogeneous disease for which natural history can be predicted based… (More)
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2000
2000
Human Dermo-1 has attributes similar to twist in early bone development.
Basic helix-loop-helix (bHLH) transcription factors are implicated in cell lineage determination and differentiation. Dermo-1… (More)
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Highly Cited
1999
Highly Cited
1999
Twist is a potential oncogene that inhibits apoptosis.
Oncogene activation increases susceptibility to apoptosis. Thus, tumorigenesis must depend, in part, on compensating mutations… (More)
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