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Significance Targeting specific genomic loci with synthetic molecules remains a major goal in chemistry, biology, and precision… Expand Background: We searched for novel regulators of insulin-stimulated glucose transport in adipocytes. Results: Tumor suppressor… Expand Objective Failure to properly dispose of glucose in response to insulin is a serious health problem, occurring during obesity and… Expand Recently, a 17p13.3 microdeletion syndrome characterized by significant postnatal growth retardation, mild to moderate mental… Expand Mammalian hibernation is a complex phenotype involving metabolic rate reduction, bradycardia, profound hypothermia, and a… Expand Background: Deletions in the 17p13.3 region are associated with abnormal neuronal migration. Point mutations or deletion copy… Expand Tumor suppressor candidate 5 (TUSC5) is a gene expressed abundantly in white adipose tissue (WAT), brown adipose tissue (BAT… Expand Tumor suppressor candidate 5 (Tusc5, also termed brain endothelial cell derived gene-1 or BEC-1), a CD225 domain-containing, cold… Expand Rat brain endothelial cell derived gene-1 (BEC-1) had considerable homology with tumor suppressor candidate 5 (TUSC5). TUSC5 was… Expand The human genome has two linked α-globin genes on chromosome 16. Deletion of one or more of them, as occurs in α-thalassaemia… Expand