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TUBB3 gene

Known as: Tubulin, Beta 3 Class III Gene, TUBULIN, BETA-3, tubulin beta 3 class III 
This gene is involved in microtubule function and structure.
National Institutes of Health

Related topics

Related topics

8 relations
Cell MovementCytokinesisMicrotubule ProcessMuscle Contraction

Broader (1)

Genes

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2016
Highly Cited
2016
Two unique TUBB3 mutations cause both CFEOM3 and malformations of cortical development
One set of missense mutations in the neuron specific beta tubulin isotype 3 (TUBB3) has been reported to cause malformations of… 
Review
2015
Review
2015
Mitochondrial dynamics and inherited peripheral nerve diseases
Highly Cited
2013
Highly Cited
2013
MiR-200c and HuR in ovarian cancer
BackgroundMicroRNAs in solid malignancies can behave as predictors of either good or poor outcome. This is the case with members… 
Highly Cited
2013
Highly Cited
2013
Direct binding of TUBB3 with DCC couples netrin-1 signaling to intracellular microtubule dynamics in axon outgrowth and guidance
Summary The coupling of axon guidance cues, such as netrin-1, to microtubule (MT) dynamics is essential for growth cone… 
Highly Cited
2010
Highly Cited
2010
Mutations in the neuronal ß-tubulin subunit TUBB3 result in malformation of cortical development and neuronal migration defects.
Mutations in the TUBB3 gene, encoding β-tubulin isotype III, were recently shown to be associated with various neurological… 
Highly Cited
2010
Highly Cited
2010
Evidence of an asymmetrical endophenotype in congenital fibrosis of extraocular muscles type 3 resulting from TUBB3 mutations.
PURPOSE Orbital magnetic resonance imaging (MRI) was used to investigate the structural basis of motility abnormalities in… 
Highly Cited
2008
Highly Cited
2008
Proteomic characterization of cytoskeletal and mitochondrial class III β-tubulin
Class III β-tubulin (TUBB3) has been discovered as a marker of drug resistance in human cancer. To get insights into the… 
Highly Cited
2007
Highly Cited
2007
Class III β‐tubulin, a marker of resistance to paclitaxel, is overexpressed in pancreatic ductal adenocarcinoma and intraepithelial neoplasia
Aims:  Class III β‐tubulin (TUBB3) reduces microtubule stability and confers resistance to microtubule‐stabilizing taxanes… 
2002
2002
Congenital fibrosis of the vertically acting extraocular muscles maps to the FEOM3 locus
Abstract. The diagnosis of congenital fibrosis of the extraocular muscles (CFEOM) encompasses several different inherited… 
Highly Cited
1999
Highly Cited
1999
CFEOM3: a new extraocular congenital fibrosis syndrome that maps to 16q24.2-q24.3.
PURPOSE To define the clinical characteristics and determine the gene localization for a previously undescribed form of… 
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