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TUBB2A gene

Known as: TUBB2A, class IIa beta-tubulin, TUBULIN, BETA-2A 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2018
2018
Defective kinesin binding of TUBB2A causes progressive spastic ataxia syndrome resembling sacsinopathy
Microtubules participate in fundamental cellular processes, including chromosomal segregation and cell division, migration and… 
2018
2018
Differential requirements of tubulin genes in mammalian forebrain development
Tubulin genes encode a series of homologous proteins used to construct microtubules which are essential for multiple cellular… 
2017
2017
Down Regulation of the Munc18b-syntaxin-11 Complex and β1-tubulin Impairs Secretion and Spreading in Neonatal Platelets
Abstract Neonatal platelets are hyporeactive and show impaired agonist-induced secretion despite no obvious abnormalities in… 
2017
2017
De Novo TUBB2A Variant Presenting With Anterior Temporal Pachygyria
TUBB2A is a gene that has recently been reported in association with structural brain abnormalities. Only 3 cases have been… 
Highly Cited
2014
Highly Cited
2014
De novo mutations in the beta-tubulin gene TUBB2A cause simplified gyral patterning and infantile-onset epilepsy.
2013
2013
Altered TUBB3 expression contributes to the epothilone response of mitotic cells
Background:Epothilones are a novel group of microtubule (mt) targeting cancer drugs that bind to the β-subunit of the αβ-tubulin… 
2013
2013
Validation of Suitable Reference Genes for Expression Studies in Different Pilocarpine-Induced Models of Mesial Temporal Lobe Epilepsy
It is well recognized that the reference gene in a RT-qPCR should be properly validated to ensure that gene expression is… 
2012
2012
Identification of differentially expressed genes in SHSY5Y cells exposed to okadaic acid by suppression subtractive hybridization
BackgroundOkadaic acid (OA), a toxin produced by several dinoflagellate species is responsible for frequent food poisonings… 
2011
2011
Regulation of β‐tubulin isotypes by micro‐RNA 100 in MCF7 breast cancer cells
Antimitotic drugs are key components of combination chemotherapy protocols for hematological and solid tumors. The taxanes (e.g… 
2008
2008
Gene expression profile of mouse prostate tumors reveals dysregulations in major biological processes and identifies potential murine targets for preclinical development of human prostate cancer…
Translation of preclinical studies into effective human cancer therapy is hampered by the lack of defined molecular expression… 
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