TSG101 gene

Known as: VPS23, VACUOLAR PROTEIN SORTING 23, YEAST, HOMOLOG OF, tumor susceptibility 101 
This gene is involved in suppression of transcription and regulation of the cell cycle. It also plays a role in cell proliferation and survival.
National Institutes of Health

Papers overview

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Highly Cited
2013
Highly Cited
2013
Exosomes are extracellular vesicles (EVs) secreted upon fusion of endosomal multivesicular bodies (MVBs) with the plasma membrane… (More)
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Highly Cited
2010
Highly Cited
2010
Agonist MHC-peptide complexes in the immunological synapse (IS) signal through T cell receptor (TCR) microclusters (MCs) that… (More)
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Highly Cited
2007
Highly Cited
2007
A null mutation in the gene encoding the putative E3 ubiquitin-protein ligase Mahogunin causes spongiform neurodegeneration, a… (More)
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2007
2007
Rta, an Epstein-Barr virus (EBV)-encoded immediate-early protein, governs the reactivation of the viral lytic program by… (More)
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Highly Cited
2005
Highly Cited
2005
The early endosome comprises morphologically distinct regions specialised in sorting cargo receptors. A central question is… (More)
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Highly Cited
2002
Highly Cited
2002
Efficient budding of HIV-1 from the plasma membrane of infected cells requires the function of a 6-kDa protein known as p6. A… (More)
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2002
2002
Functional inactivation of tumor susceptibility gene tsg101 leads to cellular transformation and tumorigenesis in mice. While… (More)
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Highly Cited
2001
Highly Cited
2001
Class E vacuolar protein sorting (vps) proteins are required for appropriate sorting of receptors within the yeast endocytic… (More)
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1998
1998
TSG101 is a recently discovered tumor susceptibility gene whose functional inactivation in mouse fibroblasts results in cell… (More)
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1997
1997
Recent work has identified a mouse gene (tsg101) whose inactivation in fibroblasts results in cellular transformation and the… (More)
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