Skip to search formSkip to main contentSkip to account menu

TRPM3 protein, human

Known as: melastatin 2, human, LTrpC-3, Long Transient Receptor Potential Channel 3 
Transient receptor potential cation channel subfamily M member 3 (1732 aa, ~198 kDa) is encoded by the human TRPM3 gene. This protein is involved in… 
National Institutes of Health

Related topics

Related topics

14 relations
Cellular MembraneIntegral Membrane ProteinsIon ChannelIon Channel Protein Gene

Broader (1)

TRPM Cation Channels

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2015
Highly Cited
2015
The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment
In Alzheimer's disease, accumulation of soluble oligomers of β-amyloid peptide is known to be highly toxic, causing disturbances… 
Highly Cited
2015
Highly Cited
2015
Homocysteine and cytosolic GSH depletion induce apoptosis and oxidative toxicity through cytosolic calcium overload in the hippocampus of aged mice: Involvement of TRPM2 and TRPV1 channels
Review
2013
Review
2013
The TRPM2 ion channel, an oxidative stress and metabolic sensor regulating innate immunity and inflammation
TRPM2 (transient receptor potential melastatin 2) is the unique fusion of a Ca2+-permeable pore with an enzymatic domain that… 
Review
2013
Review
2013
TRP channels and analgesia.
Highly Cited
2013
Highly Cited
2013
Neutrophil TRPM2 channels are implicated in the exacerbation of myocardial ischaemia/reperfusion injury.
AIMS Transient receptor potential melastatin 2 (TRPM2) highly expressed in immunocytes is a Ca(2+)-permeable non-selective cation… 
Highly Cited
2012
Highly Cited
2012
Cell Death and Autophagy under Oxidative Stress: Roles of Poly(ADP-Ribose) Polymerases and Ca2+
ABSTRACT On the cellular level, oxidative stress may cause various responses, including autophagy and cell death. All of these… 
Highly Cited
2011
Highly Cited
2011
Dendritic cell maturation and chemotaxis is regulated by TRPM2‐mediated lysosomal Ca2+ release
Chemokines induce calcium (Ca2+) signaling and chemotaxis in dendritic cells (DCs), but the molecular players involved in shaping… 
Highly Cited
2011
Highly Cited
2011
Transient Receptor Potential Melastatin 2 (TRPM2) ion channel is required for innate immunity against Listeria monocytogenes
The generation of reactive oxygen species (ROS) is inherent to immune responses. ROS are crucially involved in host defense… 
Highly Cited
2010
Highly Cited
2010
Identification of Direct and Indirect Effectors of the Transient Receptor Potential Melastatin 2 (TRPM2) Cation Channel*
Transient receptor potential melastatin 2 (TRPM2) is a Ca2+-permeable cation channel involved in physiological and… 
Highly Cited
2008
Highly Cited
2008
Altered functional properties of a TRPM2 variant in Guamanian ALS and PD
Two related neurodegenerative disorders, Western Pacific amyotrophic lateral sclerosis (ALS) and parkinsonism–dementia (PD… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)