TRIM5 wt Allele

Known as: RNF88, TRIM5alpha, Tripartite Motif Containing 5 wt Allele 
Human TRIM5 wild-type allele is located in the vicinity of 11p15 and is approximately 275 kb in length. This allele, which encodes tripartite motif… (More)
National Institutes of Health

Papers overview

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Highly Cited
2010
Highly Cited
2010
Simian immunodeficiency viruses of sooty mangabeys (SIVsm) are the source of multiple, successful cross-species transmissions… (More)
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Highly Cited
2009
Highly Cited
2009
New World monkeys of the genus Aotus synthesize a fusion protein (AoT5Cyp) containing tripartite motif-containing 5 (TRIM5) and… (More)
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Highly Cited
2007
Highly Cited
2007
Primate genomes contain a large number of endogenous retroviruses and encode evolutionarily dynamic proteins that provide… (More)
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Highly Cited
2007
Highly Cited
2007
TRIM5alpha provides a cytoplasmic block to retroviral infection, and orthologs encoded by some primates are active against HIV… (More)
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Highly Cited
2006
Highly Cited
2006
The primate TRIM5 proteins constitute a class of restriction factors that prevent host cell infection by retroviruses from… (More)
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Highly Cited
2006
Highly Cited
2006
The primate TRIM5alpha proteins have recently been defined as cellular restriction factors, preventing primate infection by… (More)
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Highly Cited
2005
Highly Cited
2005
Primate genomes encode a variety of innate immune strategies to defend themselves against retroviruses. One of these, TRIM5alpha… (More)
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Highly Cited
2005
Highly Cited
2005
The peptidyl-prolyl isomerase cyclophilin A (CypA) embraces an exposed, proline-rich loop on HIV-1 capsid (CA) and renders… (More)
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Highly Cited
2005
Highly Cited
2005
The tripartite motif 5alpha protein (TRIM5alpha) is one of several factors expressed by mammalian cells that inhibit retrovirus… (More)
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Highly Cited
2004
Highly Cited
2004
Replication of HIV-1 and N-tropic murine leukemia virus (N-MLV) is restricted in a number of different primate cells. In some… (More)
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