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TRIM5 wt Allele

Known as: RNF88, TRIM5alpha, Tripartite Motif Containing 5 wt Allele 
Human TRIM5 wild-type allele is located in the vicinity of 11p15 and is approximately 275 kb in length. This allele, which encodes tripartite motif… Expand
National Institutes of Health

Papers overview

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Highly Cited
2007
Highly Cited
2007
The human tripartite motif (TRIM) family comprises 70 members, including HIV restriction factor TRIM5α and disease-associated… Expand
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Highly Cited
2006
Highly Cited
2006
The host restriction factor TRIM5alpha mediates species-specific, early blocks to retrovirus infection; susceptibility to these… Expand
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Highly Cited
2006
Highly Cited
2006
The primate TRIM5alpha proteins have recently been defined as cellular restriction factors, preventing primate infection by… Expand
Highly Cited
2006
Highly Cited
2006
ABSTRACT The primate TRIM5 proteins constitute a class of restriction factors that prevent host cell infection by retroviruses… Expand
Highly Cited
2006
Highly Cited
2006
ABSTRACT Recent studies have revealed the contribution of TRIM5α to retrovirus restriction in cells from a variety of primate… Expand
Highly Cited
2005
Highly Cited
2005
Primate genomes encode a variety of innate immune strategies to defend themselves against retroviruses. One of these, TRIM5alpha… Expand
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Highly Cited
2005
Highly Cited
2005
Retroviral restriction factors are cellular proteins that interfere with retrovirus replication at a postpenetration… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Retroviruses encounter dominant postentry restrictions in cells of particular species. Human immunodeficiency virus type… Expand
Highly Cited
2005
Highly Cited
2005
ABSTRACT The tripartite motif 5α protein (TRIM5α) is one of several factors expressed by mammalian cells that inhibit retrovirus… Expand
Highly Cited
2004
Highly Cited
2004
The rhesus macaque tripartite motif containing protein TRIM5alpha specifically restricts HIV-1 infection at an early post-entry… Expand