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TRIM5 wt Allele

Known as: RNF88, TRIM5alpha, Tripartite Motif Containing 5 wt Allele 
Human TRIM5 wild-type allele is located in the vicinity of 11p15 and is approximately 275 kb in length. This allele, which encodes tripartite motif… Expand
National Institutes of Health

Papers overview

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Highly Cited
2009
Highly Cited
2009
Background Tripartite motif (TRIM) proteins constitute a family of proteins that share a conserved tripartite architecture. The… Expand
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Highly Cited
2006
Highly Cited
2006
The host restriction factor TRIM5alpha mediates species-specific, early blocks to retrovirus infection; susceptibility to these… Expand
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Highly Cited
2006
Highly Cited
2006
The primate TRIM5alpha proteins have recently been defined as cellular restriction factors, preventing primate infection by… Expand
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Highly Cited
2006
Highly Cited
2006
ABSTRACT The primate TRIM5 proteins constitute a class of restriction factors that prevent host cell infection by retroviruses… Expand
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Highly Cited
2005
Highly Cited
2005
Primate genomes encode a variety of innate immune strategies to defend themselves against retroviruses. One of these, TRIM5alpha… Expand
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Highly Cited
2005
Highly Cited
2005
Retroviral restriction factors are cellular proteins that interfere with retrovirus replication at a postpenetration… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Retroviruses encounter dominant postentry restrictions in cells of particular species. Human immunodeficiency virus type… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT The tripartite motif 5α protein (TRIM5α) is one of several factors expressed by mammalian cells that inhibit retrovirus… Expand
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Highly Cited
2004
Highly Cited
2004
The rhesus macaque tripartite motif containing protein TRIM5alpha specifically restricts HIV-1 infection at an early post-entry… Expand
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Highly Cited
2004
Highly Cited
2004
Replication of HIV-1 and N-tropic murine leukemia virus (N-MLV) is restricted in a number of different primate cells. In some… Expand
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