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TREX2 gene

Known as: TREX2, Three Prime Repair Exonuclease 2 Gene, 3-PRIME REPAIR EXONUCLEASE 2 
This gene is involved in DNA repair and in the maintenance of DNA integrity.
National Institutes of Health

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2014
2014
Following acute infection, herpes simplex virus (HSV) establishes latency in sensory neurons, from which it can reactivate and… Expand
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2013
2013
Replication fork maintenance pathways preserve chromosomes, but their faulty application at nonallelic repeats could generate… Expand
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Highly Cited
2012
Highly Cited
2012
Chromosomal double strand breaks (DSBs) can be repaired by a number of mechanisms that result in diverse genetic outcomes. To… Expand
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2007
2007
Three-prime repair exonucleases 1 and 2 (TREX1 and TREX2) play a role in the metabolism and clearance of DNA. The objective of… Expand
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2007
2007
Cisplatin, an anticancer drug, forms DNA interstrand cross-links (ICL) that interfere with replication, whereas TREX2 is a 3'-->5… Expand
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2004
2004
Fred W. Perrino*, Anna Krol, Scott Harvey, S. Lilly Zheng, David A. Horita, Thomas Hollis, Deborah A. Meyers, William B. Isaacs… Expand
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2002
2002
Proofreading function by the 3′→ 5′ exonuclease of DNA polymerase δ (pol δ) is consistent with the observation that deficiency of… Expand
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Highly Cited
2001
Highly Cited
2001
The excision of nucleotides from DNA 3′ termini is an important step in DNA replication, repair, and recombination pathways to… Expand
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Highly Cited
2001
Highly Cited
2001
The TREX1 and TREX2 genes encode mammalian 3′→5′ exonucleases. Expression of the TREX genes in human cells was investigated using… Expand
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Highly Cited
1999
Highly Cited
1999
The 3′→5′ exonucleases catalyze the excision of nucleoside monophosphates from the 3′ termini of DNA. We have identified the cDNA… Expand
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