TREX2 gene

Known as: TREX2, Three Prime Repair Exonuclease 2 Gene, 3-PRIME REPAIR EXONUCLEASE 2 
This gene is involved in DNA repair and in the maintenance of DNA integrity.
National Institutes of Health

Papers overview

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2013
2013
Replication fork maintenance pathways preserve chromosomes, but their faulty application at nonallelic repeats could generate… (More)
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Highly Cited
2012
Highly Cited
2012
Chromosomal double strand breaks (DSBs) can be repaired by a number of mechanisms that result in diverse genetic outcomes. To… (More)
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2011
2011
Trex2 is a 3' → 5' exonuclease that removes 3'-mismatched sequences in a biochemical assay; however, its biological function… (More)
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2009
2009
TREX2 is a 3'-->5' exonuclease that binds to DNA and removes 3' mismatched nucleotides. By an in vitro structure function… (More)
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2007
2007
Cisplatin, an anticancer drug, forms DNA interstrand cross-links (ICL) that interfere with replication, whereas TREX2 is a 3'-->5… (More)
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2004
2004
Fred W. Perrino*, Anna Krol, Scott Harvey, S. Lilly Zheng, David A. Horita, Thomas Hollis, Deborah A. Meyers, William B. Isaacs… (More)
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2002
2002
Proofreading function by the 3'-->5' exonuclease of DNA polymerase delta (pol delta) is consistent with the observation that… (More)
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2001
2001
The excision of nucleotides from DNA 3' termini is an important step in DNA replication, repair, and recombination pathways to… (More)
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2001
2001
The TREX1 and TREX2 genes encode mammalian 3'-->5' exonucleases. Expression of the TREX genes in human cells was investigated… (More)
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Highly Cited
1999
Highly Cited
1999
The 3'-->5' exonucleases catalyze the excision of nucleoside monophosphates from the 3' termini of DNA. We have identified the… (More)
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