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TRDMT1 gene

Known as: tRNA aspartic acid methyltransferase 1, TRDMT1, tRNA Aspartic Acid Methyltransferase 1 Gene 
This gene is involved in methylation of aspartic acid transfer RNA.
National Institutes of Health

Related topics

Related topics

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Methylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2012
Highly Cited
2012
Widespread occurrence of 5-methylcytosine in human coding and non-coding RNA
The modified base 5-methylcytosine (m5C) is well studied in DNA, but investigations of its prevalence in cellular RNA have been… Expand
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Highly Cited
2009
Highly Cited
2009
Retrotransposon silencing and telomere integrity in somatic cells of Drosophila depends on the cytosine-5 methyltransferase DNMT2
Here we show that the cytosine-5 methyltransferase DNMT2 controls retrotransposon silencing in Drosophila somatic cells. In… Expand
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Highly Cited
2008
Highly Cited
2008
Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism.
Although their amino acid sequences and structure closely resemble DNA methyltransferases, Dnmt2 proteins were recently shown by… Expand
Highly Cited
2007
Highly Cited
2007
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish.
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA… Expand
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Highly Cited
2006
Highly Cited
2006
Methylation of tRNAAsp by the DNA Methyltransferase Homolog Dnmt2
The sequence and the structure of DNA methyltransferase-2 (Dnmt2) bear close affinities to authentic DNA cytosine… Expand
Highly Cited
2003
Highly Cited
2003
Endogenous Assays of DNA Methyltransferases: Evidence for Differential Activities of DNMT1, DNMT2, and DNMT3 in Mammalian Cells In Vivo
ABSTRACT While CpG methylation can be readily analyzed at the DNA sequence level in wild-type and mutant cells, the actual DNA… Expand
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Highly Cited
2003
Highly Cited
2003
The Human Dnmt2 Has Residual DNA-(Cytosine-C5) Methyltransferase Activity*
The human Dnmt2 protein is one member of a protein family conserved from Schizosaccharomyces pombe and Drosophila melanogaster to… Expand
Highly Cited
1998
Highly Cited
1998
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases
Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases 
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Highly Cited
1998
Highly Cited
1998
A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast.
Trace levels of 5-methylcytosine persist in the DNA of mouse embryonic stem cells that are homozygous for null mutations in Dnmt1… Expand
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Highly Cited
1998
Highly Cited
1998
Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells.
We have shown previously that de novo methylation activities persist in mouse embryonic stem (ES) cells homozygous for a null… Expand
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