Skip to search formSkip to main contentSkip to account menu

TRDMT1 gene

Known as: tRNA aspartic acid methyltransferase 1, TRDMT1, tRNA Aspartic Acid Methyltransferase 1 Gene 
This gene is involved in methylation of aspartic acid transfer RNA.
National Institutes of Health

Related topics

Related topics

1 relation
Methylation

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2014
Highly Cited
2014
Genome methylation in D. melanogaster is found at specific short motifs and is independent of DNMT2 activity
Cytosine methylation in the genome of Drosophila melanogaster has been elusive and controversial: Its location and function have… 
2013
2013
Target recognition, RNA methylation activity and transcriptional regulation of the Dictyostelium discoideum Dnmt2-homologue (DnmA)
Although the DNA methyltransferase 2 family is highly conserved during evolution and recent reports suggested a dual specificity… 
Highly Cited
2013
Highly Cited
2013
The RNA methyltransferase Dnmt2 is required for efficient Dicer-2-dependent siRNA pathway activity in Drosophila.
Highly Cited
2008
Highly Cited
2008
Human DNMT2 methylates tRNA(Asp) molecules using a DNA methyltransferase-like catalytic mechanism.
Although their amino acid sequences and structure closely resemble DNA methyltransferases, Dnmt2 proteins were recently shown by… 
Highly Cited
2007
Highly Cited
2007
Dnmt2 functions in the cytoplasm to promote liver, brain, and retina development in zebrafish.
The roles of DNA methyltransferase-2 (DNMT2) enzymes are controversial; whether DNMT2 functions primarily as a nuclear DNA… 
Highly Cited
2003
Highly Cited
2003
The Human Dnmt2 Has Residual DNA-(Cytosine-C5) Methyltransferase Activity*
The human Dnmt2 protein is one member of a protein family conserved from Schizosaccharomyces pombe and Drosophila melanogaster to… 
Highly Cited
2003
Highly Cited
2003
Endogenous Assays of DNA Methyltransferases: Evidence for Differential Activities of DNMT1, DNMT2, and DNMT3 in Mammalian Cells In Vivo
ABSTRACT While CpG methylation can be readily analyzed at the DNA sequence level in wild-type and mutant cells, the actual DNA… 
Highly Cited
2001
Highly Cited
2001
Structure of human DNMT2, an enigmatic DNA methyltransferase homolog that displays denaturant-resistant binding to DNA.
DNMT2 is a human protein that displays strong sequence similarities to DNA (cytosine-5)-methyltransferases (m(5)C MTases) of both… 
Highly Cited
1998
Highly Cited
1998
A candidate mammalian DNA methyltransferase related to pmt1p of fission yeast.
Trace levels of 5-methylcytosine persist in the DNA of mouse embryonic stem cells that are homozygous for null mutations in Dnmt1… 
Highly Cited
1998
Highly Cited
1998
Dnmt2 is not required for de novo and maintenance methylation of viral DNA in embryonic stem cells.
We have shown previously that de novo methylation activities persist in mouse embryonic stem (ES) cells homozygous for a null… 
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)