TRAF4 protein, human

Known as: TNF Receptor-Associated Factor 4, Metastatic Lymph Node Gene 62 Protein, Tumor Necrosis Receptor-Associated Factor 4 
TNF receptor-associated factor 4 (470 aa, ~54 kDa) is encoded by the human TRAF4 gene. This protein plays a role in the modulation of TNF receptor… (More)

Topic mentions per year

Topic mentions per year

1996-2018
051019962018

Papers overview

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2013
2013
TGF-β signaling is a therapeutic target in advanced cancers. We identified tumor necrosis factor receptor-associated factor 4… (More)
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2011
2011
BACKGROUND Reactive oxygen species generation is one consequence of ligand engagement of platelet glycoprotein (GP) receptors… (More)
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2007
2007
Tumor necrosis factor receptor (TNFR) associated factor 4 (TRAF4) was initially identified as a gene amplified and overexpressed… (More)
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2007
2007
The MAPK kinase kinase MEKK4 is required for neurulation and skeletal patterning during mouse development. MEKK4 phosphorylates… (More)
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Highly Cited
2005
Highly Cited
2005
Tumor necrosis factor alpha (TNF-alpha) receptor-associated factors (TRAFs) play important roles in TNF-alpha signaling by… (More)
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2005
2005
Toll-like receptors (TLR) and nicotinamide adenine dinucleotide phosphate (NADPH) oxidase play an essential role in intracellular… (More)
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2005
2005
TRAF4 has previously been shown to activate JNK through an unknown mechanism. Here, we show that endogenous TRAF4 and MEKK4… (More)
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2002
2002
TRAF4 belongs to the tumor necrosis factor receptor-associated factor (TRAF) family of proteins but, unlike other family members… (More)
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Highly Cited
1999
Highly Cited
1999
The common neurotrophin receptor, p75(NTR), has been shown to signal in the absence of Trk tyrosine kinase receptors, including… (More)
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Highly Cited
1998
Highly Cited
1998
Through specific interactions with members of the tumor necrosis receptor (TNFR) family, adapter molecules such as the serine… (More)
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