Cysteine-Rich Domain

The Cysteine-Rich Domain is usually found in two copies per protein. It contains up to four conserved cysteines. The family includes a subunit from… (More)
National Institutes of Health

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Highly Cited
2008
Highly Cited
2008
The amyloid-beta peptide (Abeta) plays a major role in neuronal dysfunction and neurotoxicity in Alzheimer disease. However, the… (More)
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Highly Cited
2007
Highly Cited
2007
Mammals use DNA methylation for the heritable silencing of retrotransposons and imprinted genes and for the inactivation of the X… (More)
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Highly Cited
2006
Highly Cited
2006
Increasing evidence indicates that DHHC cysteine-rich domain-containing proteins (DHHC proteins) are protein acyltransferases… (More)
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Highly Cited
2006
Highly Cited
2006
Despite recent progress in our understanding of carotenogenesis in plants, the mechanisms that govern overall carotenoid… (More)
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Highly Cited
2006
Highly Cited
2006
The GS3 locus located in the pericentromeric region of rice chromosome 3 has been frequently identified as a major QTL for both… (More)
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Highly Cited
2003
Highly Cited
2003
A severe lack of von Willebrand factor-cleaving protease (VWF-CP) activity can cause thrombotic thrombocytopenic purpura (TTP… (More)
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Highly Cited
2002
Highly Cited
2002
Protein palmitoylation has been long appreciated for its role in tethering proteins to membranes, yet the enzymes responsible for… (More)
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Highly Cited
2002
Highly Cited
2002
ADAMs are membrane-anchored proteases that regulate cell behavior by proteolytically modifying the cell surface and ECM. Like… (More)
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Highly Cited
1997
Highly Cited
1997
Convincing evidence has accumulated to identify the Frizzled proteins as receptors for the Wnt growth factors. In parallel, a… (More)
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Highly Cited
1994
Highly Cited
1994
HIRSCHSPRUNG'S disease is a genetic disorder of neural crest development affecting 1 in 5,000 births. It is characterized by the… (More)
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